18 - Gastric Pathology Flashcards
Anatomical regions of the stomach
G-E Junction Cardia Fundus Body Antrum Pylorus Duodenum
Cardia
Adjacent to the esophagus
Fundus
Above G-E junction
Body
Most of the stomach
Antrum
Beginning of the outflow tract
Pylorus
Outflow tract
Epithelium - Antrum & Pylorus
Mostly mucous glands
Also G-Cells
Epithelium - Body
Parietal Cells - IF and Protons
Chief Cells - Pepsinogen
Ruggal Folds
In Stomach!
Increase surface areaf
Layers of the gastric wall
Mucosa
Submucosa
Muscularis propria
Serosa
3 Layers of the mucosa
Epithelium
Lamina propria
Muscularis mucosa
Muscularis propria
Bidirectional
Provides propulsion
Esophagus - Serosa?
Has no serosa. Only has adventitia!
That means no mesothelial lining. Only loose connective tissue!
Body - Oxyntic Glands
Parietal Cells
Chief Cells
Parietal Cells - On Histo
Fried Egg
Chief Cells - On Histo
Bluer
Normal gastric antral mucosa - On Histo
G-Cells
G-Cells
Secrete gastrin in response to high pH
Gastrin stimulates parietal cells to increase acid production!
Gastritis - Causis
H. Pylori Infection
NSAID/other “chemical gastritis-Reactive gastropathy
Autoimmunity
