2.5 Flashcards
what would incorrect codons in mRNA cause?
the production of a faulty or absent protein, but would only affect the proteins produced from this one mRNA strand
what is the process responsible for errors leading to inherited genetic conditions?
DNA replication
What first happens to DNA in DNA replication?
the double helix unwinds and hydrogen bonds between bases break
what does DNA polymerase do in DNA replication?
links adjacent nucleotides with phosphodiester bonds in condensation reactions
what type of DNA replication is this?
semi-conservative replication
what are the three possible ways DNA could replicate?
fragmentary, semi-conservatively and conservatively
what is conservative replication?
one DNA molecule has two original parent DNA strands and the other molecule has two new strands
what is fragmentary replication?
all DNA strands are made up of a mixture of organism parent DNA nucleotides and new nucleotides
what is semi-conservative replication?
each DNA molecule contains one original parent strand and one new strand
what did Meselson and Stahl do?
used heavy and light DNA to confirm the semi conservative model
what mutations can happen?
inaccuracies with complementary base pairing or in a gamete
what is sickle cell anaemia caused by?
a substitution mutation in the haemoglobin beta gene
