243- CNS tumors Flashcards
1
Q
what is treatment based on for CNS tumors?
A
tumor biology: not just histology but also by molecular subtype.
2
Q
Can a sinlge arm phase 2 trial tells us that a therapy is effective?
A
no. Only an RCT can really prove that
3
Q
what imaging is done to look at CNS tumors
A
contrast MRI
4
Q
most common sites of primary tumor that metastasize to the brain
A
lung, breast, melanoma
5
Q
what are the main component proteins for the GBM vaccine?
A
purified tumor antigens or dendritic cells or heat shock proteins (HSP’s, his trial)
6
Q
what is a HSP?
A
chaperone for cellular proteins. present in all nucleated cells (not RBCs)
