24 - Male Reproduction Flashcards

1
Q

Spermatogenesis is a meiotic process that culminates in the formation of (DIPLOID/HAPLOID) spermatids.

A

Haploid

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2
Q

Primordial germ cells migrate into future testes and become _________.

A

Spermatogonia

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3
Q

Spermatogonia begin mitotic division at puberty and become ________ _________.

A

Primary spermatocytes

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4
Q

Primary spermatocytes complete the first half of meiosis and become ________ ________.

A

Secondary spermatocytes

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5
Q

Secondary spermatocytes complete the second half of meiosis and become _________.

A

Spermatids

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6
Q

Spermatids undergo differentiation to become _______ _______.

A

Mature sperm

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7
Q

These cells are located within the seminiferous tubules.

A

Sertoli cells

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8
Q

_______ cells act as nurse cells (sustentacular cells) that surround primary spermatocytes and “nurse” them through the process of spermatogenesis and spermatogenesis (differentiation of spermatids into mature sperm).

A

Sertoli

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9
Q

Sertoli cells form _______ from testosterone, which is thought to be important for spermiogenesis.

A

Estrogens

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10
Q

During spermatogenesis, which step first gives haploid cells?

A

End of meiosis I – Secondary spermatocytes

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11
Q

Proacrosomal vesicles coalesce to form the acrosome, which contains _________ and proteolytic enzymes.

A

Hyaluronidase

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12
Q

What moves to the base of forming flagellum and wrap around it?

A

Mitochondria

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13
Q

The excess cytoplasm that is sloughed off from the forming sperm is called the…

A

Residual body

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14
Q

Sperm cells are stored in the _______ until ejaculated. They must remain here for a minimum of 18 to 24 hours in order to gain motility.

A

Epididymis

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15
Q

Passage through the epididymis requires several (HOURS/DAYS).

A

Days

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16
Q

These are found in interstitial spaces in testes and they secrete testosterone.

A

Cells of Leydig

17
Q

Cells of Leydig are stimulated by ________ ________ secreted by the anterior pituitary.

A

Luteinizing hormone

18
Q

______ is also necessary for spermatogenesis.

A

FSH

19
Q

Male accessory glands include the…

A

Seminal vesicles

Prostate gland

20
Q

These are paired structures behind the prostate and each one is a loculated tube lined with secretory epithelium.

A

Seminal vesicles

21
Q

Seminal vesicles secrete a mucoid material that contains…

A
Fructose 
Citric acid 
Additional nutrients 
Prostaglandins 
Fibrinogen
22
Q

During emission and ejaculation, the contents of the seminal vesicles are emptied into ejaculatory ducts containing sperm. This is ______ percent of the total volume of semen.

A

60

23
Q

_______ provides energy for sperm, and ________ make cervical mucous more receptive to sperm movement and may cause retro-peristaltic contractions of uterus and fallopian tubes.

A

Fructose

Prostaglandins

24
Q

During emission and ejaculation, the prostate gland has _____ percent of the total volume of semen.

A

30

25
Q

The prostate gland has a milky fluid containing calcium, citrate ions, phosphate ions, clotting enzyme, and profibrinolysin. This fluid is slightly _______, which may help to neutralize acidity of other seminal fluids and vaginal secretions of the female.

A

Alkaline

26
Q

These are any steroid hormone that have masculinizing effects.

A

Androgens

27
Q

Androgens include…

A

Testosterone
Dihydrotestosterone
Androstenedione

28
Q

Androgens can be synthesized in the testes and adrenal glands from…

A

Cholesterol

Acetyl-CoA

29
Q

Cells of Leydig are numerous in newborn males and adult males after puberty but are almost nonexistent in testes during childhood. These cells produce…

A

Testosterone

30
Q

After secretion, 97 percent of testosterone is loosely bound with ________ or tightly bound with _______ _______.

A

Albumin

Beta globulin

31
Q

T/F. Testosterone circulates in blood for 30 minutes to several hours, then its transferred to tissues or degraded to inactive products that are subsequently secreted.

A

True

32
Q

Testosterone that enters tissues is mostly converted to _________, especially in prostate and in fetal external genitalia.

A

Dihydrotestosterone

33
Q

Testosterone that is not fixed in tissues is converted in the liver to _________ and _________. These are conjugated as either glucuronides or sulfates and excreted into the gut via bile or urine via kidneys.

A

Androsterone

Dehydroepiandrosterone

34
Q

This hormone is a 10-amino acid peptide produced by neurons located in the arcuate nuclei of the hypothalamus. It is transported to the anterior pituitary via the hypothalamic-hypophyseal system. It stimulates the anterior pituitary to produce LH (mostly) and FSH (gonadotropic hormones).

A

Gonadotropin-Releasing hormone (GnRH)

35
Q

This hormone is a glycoprotein that activates cAMP second messenger system in target tissues and causes sertoli cells to secrete testosterone. Testosterone has a negative feedback effect on the hypothalamus.

A

Luteinizing Hormone (LH)

36
Q

This is secreted by sertoli cells and inhibits secretion of FSH by the anterior pituitary. It also inhibits secretion of GnRH to a lesser extent.

A

Inhibin