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Question review > 24/03 > Flashcards

24/03 Flashcards

1
Q

What does a low C peptide indicate?

A

T1DM

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2
Q

What is the target BP for at home ambulatory monitoring?

A

<135/85

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3
Q

What is the pattern of inheritance of MODY?

A

Autosomal dominant

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4
Q

What is the most common cause of hepatocellular carcinoma in europe?

A

Hep C

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5
Q

What are investigation findings of Wilsons disease?

A

Decreased serum copper
Decreased caeruloplasmin
Increased urinary copper

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6
Q

What are investigation findings of autoimmune hepatitis?

A

Massively raised ALT and AST
Raised IgG
ANA +ve
Anti smooth muscle antibodies +ve

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7
Q

What are the clinical features of Wilsons disease?

A 
Hepatitis or liver cirrhosis
Neurological signs
Kayser-Fleischer rings
Blue nails
Haemolysis
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8
Q

What investigations are needed for multiple myeloma?

A

Serum protein electrophoresis

  • bence jones proteins in urine
  • monoclonal proteins in serum

Bone marrow biopsy- increased plasma cells
XR- raindrop skull

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9
Q

What is the management for ITP?

A

1st line= oral prednisolone
IVIG in serious situations
Splenectomy rarely used

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10
Q

What is the preferred doac in renal impairment?

A

Apixaban

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11
Q

What are investigation findings of beta thalassaemia major?

A

HbA2 raised
HbF raised
HbA reduced

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12
Q

What does a positive Coombs test indicate?

A

Autoimmune haemolysis

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13
Q

When are triptans contraindicated?

A

With history/risk of CVD or cerebrovascular disease

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14
Q

What are key features of progressive supranuclear palsy?

A

Impaired upwards gaze
Postural instability and falls
Parkinsonism
Cognitive impairment- frontal lobe

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15
Q

What are the causes of lower zone pulmonary fibrosis?

A

Idiopathic
Asbestosis
Connective tissue disorders- except ankylosing spondylitis
Drugs e.g. amiodarone

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16
Q

What is the management of low severity CAP?

A

Amoxicillin

17
Q

What is the most common causative organism of an infective exacerbation of bronchiectasis?

A

H. influenzae

18
Q

What are features of hypokalaemia on ECG?

A 
U waves
Flattened T waves 
Prolonged PR interval
Long QT
ST depression
19
Q

What is the treatment of torsades des pointes?

A

IV magnesium sulphate

Question review (16 decks)

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