23b Amygdala, Hippocampal, Limbic - Emotion/Cognition Flashcards

1
Q

What amygdaloid nucleus controls oflaction?

A

corticomedial

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2
Q

What amygdaloid nucleus is the principal output nuclesu that is important for anutonomic control and most like the striatum?

A

central nucleus

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3
Q

What amygdaloid nucleus is the prinicipal input, assoicated with neocortex and thalamus?

A

basolateral

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4
Q

Which amygdaloid nucleus contails largest and best differentiated pyramidal cells?

A

basolateral

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5
Q

Which amygdaloid nucleus is prinicpally made up of medium spiny GAGAergic neurons with a high density of dopamine containing axons?

A

central nucleus

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6
Q

What is primary output of corticomedial nucleus?

A

primary output to hypothalamus via stria terminalis

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7
Q

What is major input source of central nucleus?

A

basolateral nuclei and hypothalamus

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8
Q

What is major output of central nucleus?

A

to brainstem and hypothalamus to regulate autonomics

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9
Q

What is main output of basolateral nucleus?

A

central nucleus. Also to prefrontal cortex and reward circuits in nucleus accumbens and striatum

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10
Q

What forms the only assocaiton between amygdaloid nuclei and hippocampus?

A

projections from basolateral nuclei to entrohinal cortex (ERC) and subiculum

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11
Q

What will a bilateral amygdala lesion cause?

A

hypersexual, tame or placid, feeding disorders, and hyperorality.

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12
Q

If basolateral is lesioned, what will happen to appetite? Central?

A

patient will eat all the time if basolateral is lesioned.

anorexia if central is lesioned.

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13
Q

What is Kluver-Bucy syndrome?

A

bilateral loss of anterior temporal lobes. Hypersexual, orallity, tame/placid, hyperphagia, hyperactive, psychic blindiness (inability to recognize emotions)

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14
Q

What is Urbech- Wiethe disease?

A

calcification o fneural tissue in anterior temporal lobes. Cant recognize fear on faces

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15
Q

What are principal cells of dentate gyrus?

A

granule cells (glutamaterigic excitatory)

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16
Q

What is cornus ammoni (CA)?

A

ram’s horn of pyramidal cell layer. The hippocampus proper.

17
Q

What part of cortex are CA fields and subiculm in?

A

allocortex

18
Q

What is main input to dentate gyrus?

A

entorhinal cortex?

19
Q

What is main output to dentate gyrus?

A

CA3

20
Q

What is the tri-synaptic circuit?

A

ERC via perforant path->DG via mossy fibers->CA3 via schaeffer collaterals->CA1

21
Q

What do mossy fibers connect?

A

DG projections to CA3 in tri-synaptic pathway

22
Q

What does perforant pathway connect?

A

ERC to dentage gyrus in tri-syn path

23
Q

What do schaeffer collaterals connect?

A

CA3 to CA1 in tri-syn path