2.3 Flashcards

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1
Q

What are the advantages of sexual reproduction?

A
  • greater genetic variation within sexually reproducing organisms
  • provides some organisms with ability to adapt to changing conditions or survive new strains of disease
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2
Q

What are the disadvantages of sexual reproduction?

A
  • half of population unable to produce offspring (males)
  • each parents only able to pass 50% of genetic material rather than 100%
  • gamete formation is random, disrupting successful parental genomes
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3
Q

What gives sexually reproducing organisms a better chance of surviving selection pressures?

A

genetic variation gives raw material for adaptation

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4
Q

How does sexual reproduction affect co-evolutionary relationship between parasite and host?

A

If host reproduces sexually, genetic variability in offspring reduces chances that all will be susceptible to parasite infections

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5
Q

What are the advantages of asexual reproduction?

A
  • whole genomes passed from parent to offspring
  • maintaining parent genome is and advantage in very narrow, stable niches or when re-colonising disturbed habitats
  • faster method, 1 member of species needed
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6
Q

What are disadvantages of asexual reproduction?

A
  • all offspring genetically identical (clones)
  • if one gets infected, it spreads quickly
  • not able to easily adapt to environmental changes, but mutations can occur, to provide variation and enable natural selection and evolution to occur
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7
Q

What do organisms that reproduce asexually have mechanisms for?

A

horizontal gene transfer between individuals to increase variation
e.g. plasmids of bacteria and yeasts

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8
Q

What is horizontal gene transfer?

A

prokaryotes can exchange genetic material within the same generation (horizontally), resulting in faster evolutionary change than in vertically transferring organisms (between generations)

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9
Q

What are examples of asexual reproduction in eukaryotes?

A

vegetative cloning in plants and parthenogenesis in lower plants and animals that lack fertilisation

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10
Q

What is benefit of asexual reproduction?

A

offspring can be produced more often and in larger numbers

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11
Q

What is parthenogenesis?

A

the development of an unfertilised egg into adult organism without egg/sperm fusion
the offspring will be haploid

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12
Q

What is vegetative propagation?

A

eukaryotic plants have ability to produce offspring from 1 parent plant
Tubers - potatoes
Bulbs - daffodils
Offsets - aloe vera
Runners - strawberries

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13
Q

Where is eukaryotic asexual reproduction more common?

A

in cooler climates that are disadvantageous to parasite or regions of low parasite density or diversity

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14
Q

What are homologous chromsomes?

A

chromosomes that are:
- same size
- same centromere position
- same gene sequence at same loci

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15
Q

What is meiosis?

A

the division of nucleus to form haploid gametes from a diploid gametocyte (not a cycle)
mechanism where variation is increased

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16
Q

Where does meiosis take place in animals?

A

ovaries and testes

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17
Q

Where does meiosis take place in plants?

A

ovaries and anthers

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18
Q

What is the first stage of meiosis I

A

Pairing of homologous chromosomes

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19
Q

Describe the pairing of homologous chromosomes…

A

chromosomes (replicated prior) consist of two identical chromatids attached at centromere
chromosomes condense and homologous pairs pair up
chiasmata form at points of contact between non-sister chromatids and DNA sections are exchanged

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20
Q

Describe crossing over…

A

human chromsomes usually have 2/3 chiasmata
crossing over is random, produces genetically recombinant chromosomes which results in new allele combinations

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21
Q

Describe the second stage of meiosis I…

A

spindle fibres attach to homologous pairs, line up at equator
orientation is completely random, each pair positioned independently irrespective of maternal/paternal origin (independent assortment)
chromosomes of each homologous pair separated to opposite poles, cytokinesis occurs and sister chromatids are no longer identical due to crossing over

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22
Q

Describe meiosis II…

A

each cell is now haploid (one copy of each homologous chromosomes, though has two sets of genetic info)
nuclear membrane breaks down, each of the two cells produced in meiosis I undergoes further division where sister chromatids of each chromosome are separated
total of 4 haploid cells are produced

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23
Q

What happens after meiosis in human males?

A

each haploid cell develops to form a sperm cell

24
Q

What happens after meiosis in human females?

A
  • meiosis I occurs in last 3 months before birth
  • only one of the cells develops further
  • after egg cell released from ovary it will not undergo meiosis II until sperm nucleus has entered
  • nucleus of only one new cell will fuse with sperm nucleus
25
Q

What is independent assortmen?

A

the alignment of homologous chromosome pairs are random leading to variation in haploid cells at end of meiosis II

26
Q

What are the sources of variation in meiosis?

A
  • crossing over
  • independent assortment
  • sexual reproduction
27
Q

What are linked genes?

A

genes on the same chromosome

28
Q

What creates recombinants?

A

separated linked genes through crossing over

29
Q

What is recombination used for?

A

scientists use frequency of recombination to map chromosomes, working out where each gene is in relation to others, pinpointing exact locations on chromosomes

30
Q

What does recombination frequency correlate with?

A

the distance between gene loci on chromosome

31
Q

How is sex determined?

A

by presence of sex chromsomes

32
Q

Explain sex chromosomes in mammals…

A

in live-bearing mammals (not marsupials) females have 2 large X chromosomes and males have one X chromosome and a smaller y chromosome
this also applies to drosophila melanogaster (fruit fly), which is unusual for insects

33
Q

What and where is the SRY gene

A

on the Y chromosome in most mammals, it determines male characteristic development
SRY = Sex determining Region of Y chromosome

34
Q

What is the default human embryonic development?

A

female

35
Q

What are does SRY gene do?

A

it is a ‘master switch’, produces transcription factor to switch on other genes, many of which are on autosomes but are only transcribed due to SRY control in males

36
Q

What are some rare congenital intersex conditions?

A
  • XX male due to SRY gene translocated to X-chromosome
  • XY female due to SRY deletion from Y-chromosome
37
Q

What leads to sex linkage?

A

heterogametic (XY) males lack most of corresponding homologous alleles in shorter Y chromosome

38
Q

How can X chromosomes mask sex linked conditions?

A

in XX females, a recessive alleles on one X can be masked by a dominant allele on others
in XY males, a recessive allele on X has no second copy to mask effects

39
Q

What does homogametic mean?

A

all gametes produced have same chromosome combination (human females)

40
Q

What does heterogametic mean?

A

gamete produced have two possible chromosome combinations (human males)

41
Q

Name examples of sex linkage…

A
  • red-green colour blind
  • haemophilia
  • duchenne muscular dystrophy
  • rickets (dominant allele)
42
Q

Explain dosage compensation…

A

in homogametic females one X is randomly partially inactivated at early stage of development which prevents double dose of gene products, this could be harmful to cells

43
Q

Explain carrier females…

A
  • carrier less likely affected by deleterious mutations on X chromosome
  • carrier unaffected as working gene copy in half of cells in all tissue
  • due to random X-inactivation, XX female has mosaic of cells with different X active an inactive
44
Q

What are mosaics?

A

only female cats can be tortoiseshell, show mosaic in fur as coats colour gene is found on X

45
Q

What are hermaphrodites?

A

species that have functioning male and female reproductive organs in each individual, they produce both male and female gametes which are exchanged with a partner

46
Q

What is the benefit of being a hermaphrodite?

A

benefit is that is encountering a partner is uncommon, no requirement for partner to opposite sex

47
Q

Give examples of hermaphrodites…

A
  • many flowers
  • earthworms
  • most land molluscs
48
Q

What affects sex ratio?

A

temperature, parasites and competition

49
Q

How does temperature affect sex ratio?

A

during egg incubation, in some reptiles it determines whether male or female

50
Q

How do parasite affect sex ratio?

A
  • some arthropods (mainly insects) sex ratio affected by infection of bacteria genus wolbachia
  • some have chromosomal sex determination but bacteria kills males or femenizes them
  • other entirely rely on parasites
51
Q

How does competition affect sex ratio?

A

some species actively change sex ratio of offspring

52
Q

Give examples of competition affected sex ratio in group living fish…

A

clown fish live in groups with dominant female and many small males
- if female removed, largest male becomes female
blue-headed wrasse have one male and many females
- removal of male causes largest female to grow twice as large and change colour

53
Q

How does aromatase influence sex ratio?

A

an enzyme that control hydrogen : oestrogen ratio

54
Q

What changes sex as it gets larger?

A

sea anemone (metridium senile), male -> female as it gets larger

55
Q

Explain sex change in mayfly through parasitisation…

A

-nematode parasitises larvae of mayfly
- female becomes sterile
- some males become intersex or female
all parasitised act as females when adult and crawl into water to lay eggs which allows parasite to parasitise next generation.