22.6.2013 (45) Flashcards

0
Q

FDA approved indications for modafinil

A

Narcolepsy
Shift work sleep disorder
OSA

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1
Q

Enzymes in oxidoreductase family

A
Oxygenase
Peroxidase
Catalase
Dehydrogenase
Oxidase
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2
Q

Basic and polar amino acids

A

Lysine
Histidine
Arginine

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3
Q

Aminoacids with acidic and polar side chains

A

Aspartic acid

Glutamic acid

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4
Q

Aminoacids with uncharged and polar side chains

A
Asparagine
Glutamine
Serine
Threonine
Tyrosine
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5
Q

Fat containing breast lesions

A
Lipoma
Oil cyst
Traumatic fat necrosis(traumatic lipid cyst)
Hamartoma
Galactocele
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6
Q

Most common thrombosis in PNH

A

Budd chiari

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7
Q

Polymerase involved in DNA proof reading and repair

A

Type II

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8
Q

DNA polymerase involved in leading strand synthesis

A

Polymerase III

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9
Q

DNA polymerase involved in gap filling and lagging strand synthesis

A

Polymerase I

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10
Q

Anti cancer drug acting on G1-S phase

A

Etoposide

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11
Q

Anti cancer drug acting on S phase

A

Antimetabolites

Hydroxy urea

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12
Q

Anti cancer drugs acting on G2-M phase

A

Bleomycin
Etoposide
Topotecan

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13
Q

Anti cancer drugs acting on M phase

A

Vinca alkaloids
Taxanes
Ixabepilone
estramustine

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14
Q

Nitrogen mustards

A
Cyclophosphamide 
Ifosfamide 
Chlorambucil
Mechlorethamine
Melphalen
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15
Q

Lipoprotein lipase is absent in

A

Liver

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16
Q

Maltese cross

A

Babesia
Cryptococcosis
Lipid in urine

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17
Q

Graph used to represent nominal and ordinal data

A

Bar graph

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18
Q

Graph used to represent interval/ratio data

A

Histogram

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19
Q

Salmonella infection for which humans are only reservoir

A

Salmonella paratyphi A

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20
Q

Drugs interfering with folic acid absorption

A
Phenytoin
Phenobarbitone 
Primadone
Sulfasalazine
Trimethoprim sulfamethoxazole
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21
Q

Drugs inhibiting dihydrofolate reductase

A
Methotrexate
Pyrimethamine
Triamterene
Pentamidine 
Trimethoprim
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22
Q

Cephalosporins that can be given in renal failure

A

Cefoperazone
Ceftriaxone
Cefopiramide

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23
Q

Tetracyclines that can be given in renal failure

A

Doxycycline

Minocycline

24
Q

Fluroquinolones that can be given in renal failure

A

Trovafloxacin

Grepafloxacin

25
Q

Anti tubercular drugs that can be given in renal failure

A

Rifampicin

26
Q

Drugs used against anaerobic infection that can be used in renal failure

A

Metronidazole

Clindamycin

27
Q

Drugs that can be given in renal failure

A
Macrolides
Chloramphenicol 
Linezolid
Quinpristin/dalfopristin
Nafcillin/oxacillin
28
Q

Apoproteins that modulate lipoprotein lipase

A

Apo A-II and C-III inhibits

Apo C-II C-1 stimulates

29
Q

Lipoprotein that activates LCAT

A

Apo A 1(also binds to HDL receptor)

30
Q

Inhibitor of CETP

A

apo C 1

31
Q

Diff btw ocular ischemic syndrome and CRVO

A
Veins are tortuous and dilated 
Retinal artery perfusion perfusion is normal
Optic disc swollen
Choroidal filling normal
Severe retinal hemorrhages
32
Q

Possibility of malignancy of gall bladder polyp

A
Age greater than 50yrs
Single polyp
Sessile polyp
Poly greater than 1cm
Rapid change in size
Associated gall stones
33
Q

Diastolic arterial pressure in young subjects is maintained by

A

High elastin content in aorta

34
Q

C.trachomatis causing endemic blinding trachoma

A

A,B,Ba,C

35
Q

C.trachomtis causing inclusion conjunctivitis

A

D to K

Also causes infant pneumonia,genital chlamydiasis

36
Q

C.trachomatis causing LGV

A

L1,L2,L3

37
Q

Primary cutaneous disorder causing non scarring alopecia

A
Telogen effluvium
Anagen effluvium
Trichotillomania
Tenia capitis
Alopecia areata
Androgenic alopecia
38
Q

Systemic diseases causing non scarring alopecia

A
SLE
secondary syphilis(tertiary syphilis causes scarring alopecia)
Hypopitutaryism 
Hypothyroidism
Hyperthyroidism
Deficiency of Fe,Zn,biotin,protein
Alopecia universalis
Ectodermal dysplasia
39
Q

Causes of restless leg syndrome

A

1.idiopathic
2.iron deficiency Anemia
3.CRF
Pregnancy
Peripheral neuropathy
Diabetic neuropathy
MS
parkinson disease
Caffeine
Antipsychotics
Barbiturates
Benzodiazepine
Alcohol

40
Q

Diff btw anaphylaxis and angioneurotic Edema

A

Vascular collapse and pruritis absent in angioneurotic edema

41
Q

Factors which decrease 2,3 BPG

A

Acidosis
Stored blood
HbF

42
Q

Zinc toxicity causes

A

Pulmonary fibrosis

43
Q

Iodine toxicity causes

A

Acne

44
Q

Most common collagen vascular disease associated with autoimmune Hemolytic Anemia

A

SLE

45
Q

Positive regulator in Lac operon

A

CAP(catabolite activator protein)

46
Q

Negative regulator of Lac operon

A

Lac I gene

47
Q

Triple assessment in Ca breast

A

Clinical exam
Mammography/USG
FNAC/biopsy

48
Q

Recurrent dislocation are least common in

A

Ankle

49
Q

Tumor suppressor genes involved in colorectal cancer

A

SMAD4
APC
TGF B RII

50
Q

Features seen only in SCC of lung

A

Clubbing
Pancoast
Hypercalcemia

51
Q

Permanent impairment of finger print

A

Radiation
Electrical current
Leprosy
Graft

52
Q

Advantages of DMPA

A
Can be used in seizures
Can be safely used in lactation
Reduced risk of PID
reduced risk of ectopic pregnancy
Protects against endometrial Ca
53
Q

Component that can neither be digested nor be fermented by GIT bacteria

A

Lignin

54
Q

Components that cannot be digested but can be fermented by bacteria

A

Cellulose
Hemicellulose
Pectins
Alginates

55
Q

Hand foot syndrome

A
5 FU
Cytarabine
Capecitabine
Sorafenib
Doxorubicin
56
Q

Most common site of rupture of abdominal aortic aneurysm

A

Left Posterolateral wall

57
Q

Most common site of peripheral aneurysm

A

Popliteal artery

58
Q

Most common type of abdominal aortic aneurysm

A

Fusiform