2.2 Electrical Signals in Neurons Flashcards
Two types of electrical signals (and their differences)
Graded potentials: short communication
Action potentials: long distance
Action potential in muscles and neuron
muscle action potential
nerve action potential
upper motor neuron
type of motor neuron
synapses with the lower motor neuron farther down the CNS
to contract a skeletal muscle
membrane potential
electrical potential differerence (voltage) across the membrane
electrochemical gradient
concentration (chemical) diff + electrical difference
note: ions move from high to low conc.
Four types of ion channels
leak channels
ligand-gated channels
mechanically-gated channel
voltage-gated channel
leak channel
randomly alternate between open and close positions
Note: more K+ leak channels than Na+, and K+ is leakier,
so membrane is more permeable to K+
ligand-gated channel
open and close in response to ligand (chemical) stimulus
mechanically-gated channel
open / close depending on mechanical stimulation in the form of vibration, touch, pressure, or tissue stretching
voltage-gated channel
open / close depending on change in membrane potential (voltage)
why does the resting membrane potential exist?
bc of small buildup of (—) ions in the cytosol and (+) ions in the ECF
Resting membrane potential arises from these 3 factors
1) Unequal distribution of ions in the ECF and cytosol
—ECF is rich in Na+ and Cl-, Cytsol has K+ and phosphates attached to molecules
2) Inability of most anions to leave the cell
3) Electrogenic nature of the Na+-K+ATPases
—they expel 3 Na+ for each 2 K+ imported
—called electrogenic
graded potential and the two types
small deviation from resting membrane potential
happens when stimuli causes mechanically-gated or ligand-gated channels to open or close
—Hyperpolarizing and depolarizing: makes the membrane more or less polarized
decremental conduction
graded potentials tthat die out as they spread along the membrane
summation
graded potentials that become strong or lost longer by summating with other graded potentials
Postsynaptic potential
graded potential occurring in dendrites or cell body of a neuron in response to a neurotransmitter
receptor potentials and generator potentials
potentials that occur in sensory receptors and sensory neurons
action potential / impulse
two phases?
sequence of rapidly occurring events that decrease and reverse the membrane potential and then eventually restore it to the same resting state
- depolarizing and repolarizing phase
depolarizing phase
negative potential becomes less negative, reaches zero, and then becomes positive
repolarizing phase
membrane potential is restored to the resting state of -70mV
after-hyperpolarizing phase
membrane potential temporarily becomes more negative than the resting level
all-or-none principle
action potential that either occurs completely or not at all