1.1 Bone Tissue and Function Flashcards
Bone remodeling
the building of new bone and the breaking down of old bone tissue
What is bone made up of?
different tissues working together, such as:
bone (osseous) tissue, cartilage, dense connective tissue, epithelium, adipose tissue, and nervous tissue
Functions of bone
support protection assistance in movement mineral homeostasis red bone marrow (blood cell production) yellow bone marrow (triglyceride storage)
diaphysis
bone’s shaft or body;
the long, cylindrical, main portion of the bone
epiphyses
proximal and distal end s of the bone
metaphyses
region between the diaphysis and the epiphyses;
each metaphysis contains an epiphyseal plate
—turns into the epiphyseal line when it stops growing
articular cartilage
thin layer of hyaline cartilage covering the part of the epiphyses where the bone forms an articulation joint with another bone
reduces friction; absorbs shock at freely movable joints
lacks a perichondrium; lacks blood vessels, repair of damage is limited
periosteum
surrounds the bone surface wherever it is not covered by articular cartilage
also protects the bone
assists fracture repair
helps nourish bone tissue
serves as an attachment point
medullary cavity
hollow, cylindrical space that contains fatty yello bone marrow and many blood vessels
minimizes the weight of the bone
endosteum
single layer of bone-forming cells
lines the medullary cavity
extracellular matrix of bone
15% water, 30% collagen fibers, and 55% crystallised mineral salts
calcification
initiated by osteoblasts (bone-building cells)
mineral salts are deposited in the framework formed by collagen fibers of the extracellular matrix, they crystallize and the tissue hardens
four types of cells in bone tissue
osteoprogenitor cells
osteoblasts
osteocytes
osteoclasts
osteoprogenitor cells
unsepcialized bone stem cells
undergo cell division; results in: osteoblasts
found along inner portion of periosteum, endosteum
osteoblasts
boen-building cells
synthesize and secrete collagen fibers and other compounds
initiate calcification
surround themselves with extracellular matrix, and become trapped in their secretions and become osteocytes
osteocytes
mature bone cells; main cells in bone tissue
do not undergo cell division
maintains daily metabolism, like exchange of nutrients and wastes with the blood
osteoclasts
huge cells derived from the fusion of as many as 50 monocytes (types of White blood cells); concentrated in the endosteum
help regulate blood calcium level
compact bone tissue
strongest form of bone tissue
composed of osteons
makes up bulk of diaphyses
provides protection; resists stresses
osteons
made up of concentric lamella arranged around an osteonic canal
note: their organisation is not static but changes over time in response to the physical demands placed on the skeleton.
concentric lamellae
circular plates of extracellular matrix, surrounding blood vessels and nerves
lacunae
small spaces between the concentric lamellae
contains osteocytes
canaliculi
slender fingerlike extensions of osteocytes that radiate from the lacunae
interstitial lamellae
are fragments of older osteons that have been partially destroyed during bone remodeling/growth
found in areas between neighboring osteons
interosteonic canals
how the blood vessels and nerves from the periosteum penetrate the compact bone
circumferential lamellae
arranged around the entire outer and inner circumference of the shaft of a long bone
spongy bone tissue
also called trabecular or cancellous bone tissue
always located in the interior of the bone, protected by a covering of compact bone
trabeculae
lamellae arranged in an irregular pattern of thin columns
difference between spongy and compact bone tissue
1) spongy bone tissue is light
2) trabeculae of spongy bone tissue support and protect the red bone marrow
periosteal arteries
small arteries accompanied by nerves; enter the diaphysis through interosteonic canals and supply the periosteum and outer part of the compact bone
metaphyseal arteries
enter the metaphyses of a long bone and (along with nutrient artery) supply the red bone marrow and bone tissue of the metaphyses
Veins that carry blood away from long bone, evident in 3 places:
1) one of two nutrient veins accompany the nutrient artery and exit through the diaphysis
2) many epiphyseal veins and metaphyseal veins exit through the epiphyses and metaphyses, respectively
3) many periosteal veins accompany their respective arteries and exit through the periosteum