2.12/2.14 Cystic Fibrosis Flashcards
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- Thick, sticky mucus cannot be sweeped out of the lungs using cillia
- Microorganisms cannot be readily removed so lung infections are likely
- Mucus blocking airways limiting SA for gas exchange ie breathing difficulties
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- Tubes of the pancreas are blocked so digestive enzymes can’t enter intestines, this reduces digestion so key nutrients are not available for absorption
- Inestines are lined with thick mucus inhibiting absorptions of nutrients into blood
- Mucus can cause cysts in pancreas which inhibits the production of enzymes for digestion ie less nutrients digested
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Explain how the expression of CFTR mutation impairs the function of the reproductive system
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- Mucus is secreted to prevent infections
- It also processes sperm through the reproductive tract after intercourse
- In men; tubes of the testes are blocked, and sperm cannot reach the penis
- In women; thick cervical mucus prevents sperm reaching the oviduct to fertilise the egg
