2.1 Metabolic Pathways Flashcards
Metabolic Pathways
Integrated series of enzyme-controlled reactions
Anabolic reactions
Build complex molecules from simple building blocks and require energy
Catabolic reactions
Break down complex molecules into simple building blocks and release energy
Types of metabolic pathways
Reversible- Fermentation in animals
Irreversible- Fermentation in plants and yeast
Alternative routes
Membrane structure
Pores- allows diffusion of specific molecules across membrane
Pumps- transports molecules against the concentration gradient
Enzymes- speed up rate of biochemical reactions in cell
Induced fit
Substrate has high affinity for active site to allow it to bind together
Active site changes shape to better fit the substrate
Products formed have lower affinity for active site to allow it to leave
Enzyme can return to its original shape and is ready to bind with another substrate
Control of metabolic pathways- Inhibition
Inhibitors decrease rate of enzyme controlled reaction
Competitive inhibitor- blocks active site so substrate can’t bind
Non competitive inhibitor- binds to another part of enzyme which indirectly changes shape of active site
Feedback inhibitor- concentration of end product builds up so it binds to the enzyme