1.8 Genomic Sequencing Flashcards
Genomic sequencing
Sequencing of nucleotide bases can be determined for individual genes and entire genomes
Comparison of genomes from different species
Many genomes have been sequenced of organisms which are:
Disease-causing organisms
Pest species
Species that are important model organisms for research
Phylogenetics
Study of evolutionary relatedness of species
Phylogenetic tree requirements
DNA sequence data
Fossil records
Three domains of life
Bacteria (Prokaryotic)
Archaea (Prokaryotic)
Eukaryotes (Eukaryotic)
Molecular clocks requirements
DNA sequence data
Fossil records
Mutation rate
Pharmacogenetics- Personalised medicine
Study of genetic variation between individuals affecting their response to drugs
Personal genome can be used to select the most effective drugs to treat disease