2017 Walls 10/11 Flashcards

1
Q

4 criteria for HIE

A
  1. Apgar < 5 at 5 and 10 min
  2. Fetal UA acidemia
  3. multisystem organ failure
  4. dev of spastic quadriplegia or dyskinectic CP

MRI 24 hours after birth is very sensitive for HIE changes

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2
Q

Estrogen effects during pregnancy

A
  • maintains uterine lining
  • cervical gland hypertrophy
  • leukorrhea
  • breast growth and milk duct development
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3
Q

lab findings in DIC for

fibrinogen, platelets, d-dimer, PT/aPTT

A

low fibrinogen
thrombocytopenia
elevated d-dimer
elevated PT/aPTT

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4
Q

% of fetus with increased NT that will have an aneuploidy

what is the measurement

A

50%

> 3mm

(of the other 50% 1/2 will have major defects including heart, diaphragmatic hernia or skeletal dysplasia or other genetic syndromes. < 20 % will have a healthy live born infant)

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5
Q

most common symptom of a lactotroph microadenoma

A

amenorrhea

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6
Q

omphalocele

A

extruded viscera in the midline, covered by peritoneum and amnion

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7
Q

gastroschisis

A

full thickness defect in the abdominal wall secondary to incomplete closure of the lateral folds during the 6th week of gestation. right of the umbilicus

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8
Q

tx of CT in patients allergic to doxy? in pregnancy?

A

azithro 1g single dose
levofloxacin 500 mg PO x7 days

Pregnancy

  • prefered azithro 1 g
  • amox 500 mg TID x7 days is alt
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9
Q

turbutaline side effect

A

cardiogenic pulmonary edema

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10
Q

mesna

A

a drug used to prevent hemorrhagic cystitis during chemotherapy with Ifex

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11
Q

tx of nec fasciitis

A

treat with PCN and clindamycin

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12
Q

what day of the menstrual cycle does implantation occur

A

20-24

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13
Q

tx for CAP

A

azithromycin

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14
Q

most sensitive test for vWD

A

vW-ristocetin cofactor assay

isolated prolonged PTT not specific will correct with mixing studies

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15
Q

Male hypogonadrophic hypogonadism semen analysis finding and treatment

A

oligospermia

tx with continuous clomid

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16
Q

tx for GC in pregnant women who is allergic to cephalosporins? not preg?

A

preferred: desensitization
alt: a single 240 mg IM dose of gentamicin plus a single 2 g oral dose of azithromycin
ID consult

not preg: a single 240 mg IM dose of gentamicin plus a single 2 g oral dose of azithromycin

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17
Q

b thal vs alpha thal hgb electrophoresis

A

B- thal: HgA2 > 3.5%

alpha thal - can be normal

18
Q

absolute contraindications to methotrexate

A
  • breast feeding
  • active pulm disease
  • PUD
  • hepatitis
  • severe anemia
19
Q

after Ulipristal acetate how long before restarting OCP

A

5 days and use backup for 14 days

20
Q

McRoberts facilitates delivery by

A

changing the outlet into a more vertical axis

21
Q

High dose radiation imaging studies

A

Pelvic CT and PET scan both are 10-50 mGy fetal exposure

22
Q

Benefits of delayed cord clamping

A

improved fetal blood count
decreased need for transfusion
lower rates of intraventricular hemorrhage
improved iron stores

23
Q

most common cause of cuff cellulitis

A

BV

24
Q

what is the most common cause of a duodenal ulcer and treatment

A

H. pylori

tx: triple
amox, clarithromycin, flagyl

dx with urea breath test

25
Q

when do you start routine pneumococcal vaccination

A

65

26
Q

most cost effective test for evaluation of hyperandrogenism

A

total testosterone

27
Q

test for suspected outflow obstruction

A

MRI (check for other anomalies) assess thickness and depth of septum, and if cervix is present

28
Q

chemo drug that causes skin necrosis and ulceration if extravasation occurs

A

doxyrubicin

29
Q

1st line treatment of rhinosinusitis

A

nasal oxymetazoline (afrin)

30
Q

hsc fluid associated with pulm edema

A

normal saline

31
Q

blue vaginal lesions after a delivery

A

GTN

- MRI to look for mets

32
Q

normal vag pH

A

3.8-4.5

higher is BV, atrophy, trich

lower yeast

33
Q

donvan bodies dx and tx

A

granuloma inguinale
tx: azithromycin or tetracycline
found in tropics, non painful papules, indurated

34
Q

% of cervical cancer dx after age 65 in US

A

20%

35
Q

risk factors for wound dehiscence

A

malignancy, sepsis, Chronic lung disease (coughing), Age

36
Q

contraindications to robotic surgery

A

acute glaucoma, retinal detachment, increased intracranial pressure, ventriculoperitoneal shunts

37
Q

how does testosterone levels change during perimenopause

A

it does not change significantly from 5 years before to 7 years after menopause

38
Q

most likely neurological injury from a lateral trocar placement

A

ilioinguinal nerve - sensory deficit on mons and upper thigh

39
Q

best way to evaluate an enterocele

A

standing

40
Q

what does the HPV6 oncoprotein bind to

A

P53 and inactivates it leading to immortilization of the cell

41
Q

what does the HPV7 oncoprotein bind to

A

Rb and phosphorylates it