2014 Flashcards
Gonadal sex is determined by what week of gestation? A. At fertilization B. 7th C. 9th D. 12th
B
The testis is expected to reach the scrotal sac by what month of gestation? A. 6th B. 7th C. 8th D. 9th
B
The equivalent of the female labia majora in males is: A. Scrotal swelling B. Urethral fold C. Urethral groove D. Glans penis
A
The derivative of the Wolffian duct in females is the: A. Uterus B. Ovary C. Gartner’s duct D. Upper third of the vagina
C
Mesonephric duct is the: A. Wolffian duct B. Mullerian duct C. Urogenital sinus D. Future ureter
A
A 3 year old male was brought to the clinic and upon palpation, no testis in the right scrotal sac was found. A permanent testis was palpated at the right internal inguinal ring. This would suggest what condition? A. True undescended testis B. Ectopic testis C. Retractile testis D. Dysgenetic testis
A
A patient with Mayer-Rokitansky syndrome will have:
A. Normal ovaries
B. 46 XY karyotype
C. Infrequent association with skeletal abnormalities
D. Normal uterus
A
Principal causes of ambiguous genitalia in a child whose gonads contain testicular tissue include? A. Congenital Adrenal Hyperplasia B. Placental Aromatase Deficiency C. 5-reductase Deficiency D. Gonadal Dysgenesis
C
Which cells cause the regression of Mullerian ducts? A. Leydig B. Sertoli C. Interstitial D. Genital Ridge
B
A 15 y/o was brought up as a male. He was recently noted to have a spurt in growth and appearance of pimples on his face. No gonads were palpable but he had an enlarged phallus. Ultrasound revealed the presence of a uterus; karyotyping revealed XX. This individual’s problem is likely:
A. Male pseudohermaphroditism
B. Female pseudohermaphroditism
C. Congenital adrenal hyperplasia
D. Testicular dysgenesis
B
Which of the following will not have mullerian structures?
A. Dysgenetic males
B. Pseudohermaphrodite male
C. Patients with mixed gonadal dysgenesis
D. Pseudohermaphrodite female
B
Which structure contains the receptor for SRY antigen?
A. yolk sac
B. dorsal mesentery
C. genital ridge
D. allantois
C
Feature of Turner’s syndrome:
A. XXY
B. Normal intelligence
C. Tall stature
D. Normal ovary
B
Which of the following malformations is probably missed at menarche?
A. Imperforate hymen
B. Transverse vaginal septum
C. Longitudinal vaginal septum
D. Vaginal atresia
C
Structure that forms distal vagina
A. Cloaca
B. Urogenital sinus
C. Mullerian Duct
D. Wolffian Duct
B
Prenatal exposure to androgens after 12 weeks would cause
A. clitoral hypertrophy
B. retain urogenital sinus
C. labioscrotal fusion
D. penile urethra
A
A true hermaphrodite:
A. pure XX or XY
B. both XX and XY
C. both ovarian and testicular tissue on both gonads
D. both ovarian and testicular tissue on opposite or both gonads
D
Which of the following structures need testosterone for its development?
A. testes
B. ovaries
C. prostate glands
D. vas deferens
D
A 16 year-old with breast and pubic hair Tanner stage III consulted for absence of menses. No palpable uterus upon examination. Serum testosterone is within normal female levels. What is the diagnosis?
a. Androgen Insensitivity Syndrome
b. Congenital Absence of the Uterus
c. Turner’s Syndrome
d. Klinefelter’s Syndrome
B
Which of the ff is used in oral contraceptives?
a. Estrone
b. Ethinyl estradiol
c. Estriol
d. Equilin
B
The ff are derivatives of 19-nortestosterone progestin EXCEPT:
a. Medroxyprogesterone acetate
b. Ethynodiol diacetate
c. Levonorgestrel
d. Norethindrone
A
True for COCs and thromboembolism except:
a. Progestin only increases clotting factors
b. Past users of cocs do not have cardiovascular disease
c. Low dose cocs no effect on venous thromboembolism
d. Hypertension is risk factor for stroke in cocs
C
Which of the following is NOT a NEW progestin:
a. Norethindrone
b. Gestodene
c. Norgestimate
d. Desogestrel
A
POP pills
a. Suppresses the secretion of Gnrh
b. Induces Endometrial hypertrophy
c. Thickening of cervical mucus
d. Takes a long time for fertility to resume after withdrawal
C
What is the mechanism of action of COCs?
a. Progesterone suppresses FSH action, Estrogen suppresses LH action
b. Progesterone suppresses LH action, Estrogen suppresses FSH action
c. Progesterone suppresses FSH action, Estrogen suppresses GnRH action
d. Progesterone suppresses GnRH action, Estrogen suppresses FSH action
B
What is the chemical modification done to make estrogen orally active:
a. Addition of ethinyl group at 17 position
b. Addition of ethinyl group at 19 position
c. Removal of carbon at 17 position
d. Removal of carbon at 19 position
A
Which progestin has the least detrimental effect on lipoproteins? A. desogestrel B. levonorgestrel C. norethindrone D. mestranol
A
The risk of getting venous thromboembolism with the use of oral contraceptives is \_\_\_\_\_ as compared to the risk in pregnancy. A. 5 times greater B. 3 times greater C. The same D. ½ as great
D
Oral contraceptives are currently thought to cause which of the following congenital defects? A. limb reduction defect B. sexual ambiguity C. heart defect D. no association with any defect
D
Which is not an absolute contraindication for OCP/COC use?
A. prior thromboembolism
B. liver tumor with previous use of OCP
C. migraine headache
D. breast cancer with positive estrogen receptors
C
Which of the following is an advantage of progestin-only pills (POPs) as compared with combined oral contraceptives (COCs)?
A. fewer ovarian cysts
B. less breakthrough bleeding
C. less effect on lactation
D. lower incidence of ectopic pregnancy if method fails
C
What is a strong contraindication to progestin-only contraceptive use? A. smoking B. depression C. mild hypertension D. unexplained bleeding
D
What aspect of injectible progestin is worrisome in adolescents and young women? A. decrease in bone mineral density B. increased pelvic infection C. worsening of acne D. increase of risk of uterine cancer
C
Which of the following is an initial disadvantage of Norplant? A. Low failure rate B. Immediately effective C. High initial expense D. Prompt return to pregnancy
C
What is the efficacy of post-coital contraception? A. 25% B. 50% C. 75% D. 100%
D
Based on the two cell-two gonadotropin theory, LH primarily acts on \_\_\_ cells to produce androstenedione. A. granulosa B. theca C. arcuate nucleus D. Leydig cells
B