2012 patho Flashcards

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1
Q

BRCA-1 and BRCA-2 are associated with Breast Cancer and another condition. What is it?!

a. leukemia
b. Ovarian cancer
c. Colon cancer

A

b. Ovarian cancer

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2
Q

In acute inflammation, leukocytosis is the usual response. In which condition does leukopenia occur?

a. Typhoid ileitis
b. Acute Appendicitis
c. Acute Gastritis
d. Pyogenic meningitis
e. Lobar Pneumonia

A

a. Typhoid ileitis

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3
Q

Which of the following of the following substances has the highest affinity to radiation?

a. Leukocytes and Blood-Forming Cells
b. Hepatocytes

A

a. Leukocytes and Blood-Forming Cells

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4
Q

What is a marker for renal failure?

a. Transferrin
b. β2 - microglobulin
c. C - reactive protein
d. Albumin

A

d. Albumin

low albumin and high alpha 2 proteins present for nephrotic syndrome

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5
Q

What is the vitamin that is important for vision?

a. Vitamin C
b. Vitamin A
c. Vitamin B

A

b. Vitamin A

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6
Q

a resected intra-abdominal tumor showed skin and its appendages, bone, and fibroadipose tissue. What do we call this tumor?

a. Cystadenoma
b. Choristoma
c. Hematoma
d. Adenoma
e. Teratoma

A

e. Teratoma

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7
Q

Microscopy examination was done to the patient’s uterus. The cells were hyperchromatic and the surrounding having mitosis. What is this called?

a. Dysplasia
b. Aplasia
c. Anaplasia
d. Hyperplasia
e. Hypertrophy

A

a. Dysplasia

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8
Q

Which of these is a congenital non-genetic condition?

a. cystic fibrosis
b. diabetes mellitus
c. down syndrome
d. cerebral palsy
e. sickle cell anemia

A

d. cerebral palsy

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9
Q

Which of these proteins decrease during hemolysis?

a. haptoglobin
b. transferrin

A

a. haptoglobin

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10
Q

Which cells are predominantly found in chronic inflammation?

a. Neutrophils
b. Lymphocytes

A

b. Lymphocytes

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11
Q

A 64 year old woman with fever, chills, headache, vomitting. Brain image shows abscess in the brain. What is the most characteristic type that describes this necrosis type?!

a. Coagulative necrosis
b. Liquefactive necrosis
c. Caseous necrosis

A

b. Liquefactive necrosis

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12
Q

What is a major component of granulation tissue?

a. scar tissue
b. New blood capillaries

A

b. New blood capillaries

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13
Q

What will be the microscopic appearance of a 90-year-old man’s Kidney?

A

hyalinosis in the small arteries

its a type of arteriolosclerosis- thickening of the arteriolar wall- and is part of the ageing

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14
Q

In what disease are neutrophils the predominant cell in one-year infection?

a. Sarcoidosis
b. Osteomyelitis

A

b. Osteomyelitis

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15
Q

Psammoma bodies are found in which cancer?

a. Ovarian cancer
b. Papillary Thyroid Carcinoma
c. Leukemia

A

b. Papillary Thyroid Carcinoma

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16
Q

Is leiomyoma a benign tumor?

A

yes, it is a benign smooth muscle tumor that very rarely becomes cancer

17
Q

Where is a thrombosis most likely to occur?

a. In the axillary region
b. In the deep veins of the leg
c. In the veins of the arms

A

b. In the deep veins of the leg

18
Q

This protein is seen when stained with Congo Red and polarized. What is it?

a. Lipofuscin
b. Amyloid
c. steatosis

A

b. Amyloid

19
Q

A 45 year old woman is being investigated with hypertension condition; tests show that right kidney is smaller than normal. This is most likely due to

a. Metaplasia
b. Atrophy
c. Hypoplasia

A

b. Atrophy

20
Q

What is the translocation that occurred in CML (Chronic Myeloid Leukemia)?

a. T (9,22)
b. T (8,23)
c. T (5, 21)

A

a. T (9,22)

21
Q

What is shock?

A

the hypoperfusion of most tissue

22
Q

A child exposed to sunlight and have a defect in nucleotide excision repair. Which of the following conditions may have in the future?

a. Bloom’s Syndrome
b. Xeroderma Pigmentosum
c. Xanthoma (eruptive)
d. Tubero-eruptive Xanthomas

A

b. Xeroderma Pigmentosum

23
Q

What is the cause of a shock following general peripheral vasodilation?

a. Gram +ve bacteria
b. Gram -ve bacteria

A

b. Gram -ve bacteria

24
Q

What is the formula for calculated osmolarity?

A

2 x [Na] + [urea] + [glucose] (mM)

25
Q

A diver presented with respiratory symptoms and joint pain. what type of embolism has most likely occurred?

A

Gas Embolism

26
Q
Total cholesterol=2.4 HDL= 0.8 TG=2.2
Whats the LDL?
a. 0.5
b. 0.6
c. 0.05
d. 0.06
A

b. 0.6

LDL=TC—(HDL+TG/2.2)

27
Q

A tumor is characterized by T1N0M0. What is true?

a. there is no tumor
b. a small tumor with no lymph node involvement and no metastasis
c. a small tumor with no lymph node involvement and some metastasis

A

b. a small tumor with no lymph node involvement and no metastasis

28
Q

The MAX protein combines and forms dimer with the MAD protein during proliferation. What is the role of this dimer in the cell cycle?

A

Tumor Suppression