2011 Flashcards
1. The incidence of disease X is 1 in 3000/year. The prevalence is 1 in 1000. On the average, what is the duration of the disease? A. 3 yrs B. 10 yrs C. 33 yrs D. 50 yrs
C
A. Cumulative incidence B. Incidence density C. Point prevalence D. Period prevalence E. Not a rate
One million Filipino have tuberculosis
E
A. Cumulative incidence B. Incidence density C. Point prevalence D. Period prevalence E. Not a rate
10% of the population will develop papillary cancer of the thyroid in their lifetime.
A
A. Cumulative incidence B. Incidence density C. Point prevalence D. Period prevalence E. Not a rate
20% of Filipinos are overweight at any given time.
C
A. Cumulative incidence B. Incidence density C. Point prevalence D. Period prevalence E. Not a rate
In a study of 160 medical students, 30 experienced headache in 2 weeks of examination period.
B
A. Cumulative incidence B. Incidence density C. Point prevalence D. Period prevalence E. Not a rate
10-20% of children will have hearing loss at sometime in any year.
C
A. Cumulative incidence B. Incidence density C. Point prevalence D. Period prevalence E. Not a rate
1% of Filipino with goiter for the past 10 yrs.
D
8. Prevalence studies are useful for which of the following: A. Studies of chronic diseases B. Studies for cause and effect C. Studies for adverse drug monitoring D. All of the above
A
9. Which of the frequency measures or rates generally requires a follow-up time period? A. Point prevalence B. Period prevalence C. Incidence density D. None of the above
C
10. Frequency of a rare disease is studied with what design? A. Cross sectional study design B. Cohort study design C. Case control study D. Any of the above
C
- Which of the following is prevalence study good for?
A. Study of local epidemic of malaria
B. Study of cancer cure among patients undergoing chemotherapy
C. Study of a new test in determining coronary stenosis
D. All of the above
A
12. What is the cumulative incidence of cancer among HIV infected subjects in the example study above? A. 5 in 7 B. 5 / 21 person-years C. 28% D. None of the above
A
- Assuming there were 100 people screened for HIV infections, 50% of which were positive. 20% of the subjects with HIV infection have a concomitant venereal disease. Which of the following statement is true of the study population?
A. The prevalence of HIV is 50%.
B. The prevalence of venereal disease is 20%.
C. The prevalence of venereal disease is 10%.
D. None of the above
A
14. Smoking is an important risk factor for cancer. However, given that it takes time (induction time or period) to develop cancer that can be attributed to smoking, which of the following is the better measure of frequency for investigating causality between smoking and cancer? A. Incidence Density B. Cumulative incidence C. Point prevalence D. Period prevalence
B
15. In a fixed cohort study of 100 individuals, 10 already have heart disease at the start of the observation period. After two years, there were already 20 subjects with heart disease. What is the annual incidence of heart disease? A. 5.5% B. 10% C. 11% D. 20%
C
True of a DIAGNOSTIC TEST:
A. clinical information obtained from history
B. clinical information obtained from physical examination
C. a test performed in a laboratory
D. constellation of findings
E. all of the above
E
The probability above which diagnosis is sufficiently likely to warrant treatment: A. Test Threshold B. Treatment Threshold C. Diagnostic Threshold D. Probability Threshold E. none of the above
B
Not true of a Diagnostic Test Design: A. A form of cohort design B. Diagnostic uncertainty C. Blind comparison with an independent gold standard applied similarly to the treatment and control group D. Results of the test being evaluated should not influence the decision to perform the gold standard E. All of the above
A
THE SENSITIVE TEST:
A. is most helpful when the test result is negative (“SnOUT”)
B. when false positive results can harm patients physically, emotionally or financially
C. to confirm or “rule in” a diagnosis that has been suggested by other data
D. is rarely positive in the absence of a disease
E. none of the above
A
THE SPECIFIC TEST:
A. When probability of disease is low and purpose of test is to discover disease
B. Reason to suspect a dangerous but treatable condition
C. Important penalty for missing a disease
D. Most helpful when the test result is positive (“SpIN”)
E. None of the above
D
Performance of measurements can be described according to which characteristic: A. Validity B. Interval C. Reliability D. Only a and c are correct E. All of the above are correct
E
Validity of measurements can operationally be defined as:
A. Degree to which the tool measures what it is intended to measure
B. Results of the measurement corresponds to the true state of the phenomenon being measured
C. Established by the comparison with an accepted standard
D. Only a and c are correct
E. All of the above are correct
E
Reliability of measurements can operationally be defined as:
A. Extent to which repeated measurements of a stable phenomenon get similar results.
B. Not affected by random error or chance
C. Reproducibility, repeatability
D. Only a and c are correct
E. All of the above are correct
D
Responsiveness of measurements refers to:
A. Ability of the instrument to detect change as conditions change
B. Ability of the instrument to register very low or high values of the condition being measured
C. Specificity of measurements to detect differences
D. Only a and c are correct
E. All of the above are correct.
A
Strategies to enhance precision include:
A. Standardize procedures and methods for the measurement.
B. Train and certify those who make the observations
C. Automate the instruments
D. Only a and c are correct
E. All of the above are correct
E
Strategies to enhance accuracy include:
A. Standardize procedures and methods for the measurement.
B. Train and certify those who make the observations
C. Automate the instruments
D. Only a and c are correct
E. All of the above are correct
E
Features of statistical abnormality:
A. Based on the Gaussian distribution curve.
B. May not be valid due to overlaps in values among those with disease and those without disease
C. Will results in all diseases having the same frequency
D. Only a and c are correct
E. All of the above are correct
E
Limitations of statistical abnormality:
A. There is a general relationship between the degree of statistical unusualness and clinical disease.
B. Many measurements are due to a population based definition
C. Some extreme values are actually beneficial
D. Only a and c are correct
E. All of the above are correct
C