2009 Total Joint Arthroplasty/Joint Salvage Flashcards
Which of the following findings is a prerequisite for a high tibial valgus osteotomy for medial compartment gonarthrosis? 1. Inflammatory arthritis 2. Ligamentous instability 3. Lateral tibial subluxation 4. Preoperative arc of motion of at least 90° 5. Narrowing of the lateral compartment cartilaginous joint space
PREFERRED RESPONSE: 4 DISCUSSION: The indications for high tibial valgus osteotomy include a physiologically young age, arthritis confined to the medial compartment, 10 to 15° of varus alignment on weight-bearing radiographs, a preoperative arc of motion of at least 90°, flexion contracture of less than 15°, and a motivated, compliant patient. Contraindications include lateral compartment narrowing of the articular cartilage, lateral tibial subluxation of greater than 1 cm, medial compartment bone loss, ligamentous instability, and inflammatory arthritis. REFERENCES Naudie D, Bourne RB, Rorabeck CH, Bourne TT: The Insall Award: Survivorship of the high tibial valgus osteotomy: A 10- to 22-year followup study. Clin Orthop Relat Res 1999;367:18-27. Pellicci PM, Tria AJ Jr, Garvin KL (eds): Orthopaedic Knowledge Update: Hip and Knee Reconstruction 2. Rosemont, IL, American Academy of Orthopaedic Surgeons, 2000, pp 255-264.
What is the main benefit of using metal-backed tibial components in total knee arthroplasty? 1. Improve the conformity of the articular surfaces 2. Reduce the maximum compressive stresses on the underlying cancellous bone 3. Increase the tensile forces on the other condyle when one is loaded 4. Decrease the thickness of the polyethylene tray 5. Decrease the compressive forces on the polyethylene tray
PREFERRED RESPONSE: 2 DISCUSSION: In a normal knee, the hard subchondral bone helps to distribute loads across the joint surface. A metal-backed tibial component in total knee arthroplasty decreases the compressive stresses on the underlying, softer cancellous bone by distributing the load over a larger surface area, particularly when one condyle is loaded. Although metallic base plates also increase the tensile forces on the other condyle when one is loaded and may decrease the thickness of the polyethylene tray, these are not benefits. Compressive forces on the polyethylene tray are increased with metal backing. The conformity of the articular surfaces is not affected by metal backing of the tibial component. REFERENCE Pellicci PM, Tria AJ Jr, Garvin KL (eds): Orthopaedic Knowledge Update: Hip and Knee Reconstruction 2. Rosemont, IL, American Academy of Orthopaedic Surgeons, 2000, pp 265-274.
A 32-year-old woman with systemic lupus erythematosus treated with methotrexate and oral corticosteroids reports right groin pain with ambulation and night pain. Examination reveals pain with internal and external rotation and flexion that is limited to 105° because of discomfort. Laboratory studies show a serum WBC of 9.0/mm3 and an erythrocyte sedimentation rate of 35 mm/h. Figures 1A and 1B show AP and lateral radiographs of the right hip. Further evaluation should include 1. examination under fluoroscopy. 2. MRI. 3. a bone scan. 4. arthrography. 5. aspiration and arthrography.

PREFERRED RESPONSE: 2 DISCUSSION: The radiographs show Ficat and Arlet stage 2 osteonecrosis. The femoral head remains round, and there are sclerotic changes in the superolateral quadrant. Patients with systemic lupus erythematosus are at risk for osteonecrosis because of prednisone use and the underlying metabolic changes associated with the condition (hypofibrinolysis and thrombophilia). MRI is the best diagnostic method for detecting osteonecrosis, with a greater than 98% sensitivity and specificity. For this patient, an MRI can assess the contralateral hip for any involvement and can quantify the extent of the lesion. REFERENCES Mont MA, Jones LC, Sotereanos DG, Amstutz HC, Hungerford DS: Understanding and treating osteonecrosis of the femoral head. Instr Course Lect 2000;49:169-185. Koval KJ (ed): Orthopaedic Knowledge Update 7. Rosemont, IL, American Academy of Orthopaedic Surgeons, 2002, pp 417-451.
Which of the following factors can contribute to patellar subluxation following routine total knee arthroplasty? 1. External rotation of the femoral component 2. Internal rotation of the tibial component 3. Symmetric patellar resection 4. Lateral placement of the tibial component 5. Neutral alignment of the mechanical axis
PREFERRED RESPONSE: 2 DISCUSSION: Excessive resection of the lateral facet of the patella can lead to subluxation. Rotational alignment of the components can have a significant impact on patellar tracking. Internal rotation of the femoral component leads to more lateral alignment of the patella within the trochlear groove. Internal rotation and medial placement of the tibial component results in lateralization of the tibial tubercle with an increase in the Q angle. Excessive valgus alignment of the mechanical axis, or insufficient correction of preoperative valgus, has a similar effect on the Q angle, and both can result in a higher rate of tracking problems. REFERENCE Ayers DC, Dennis DA, Johanson NA, Pelligrini VD: Common complications of total knee arthroplasty. J Bone Joint Surg Am 1997;79:278-311.
During total knee arthroplasty using a posterior cruciate-retaining design, excessive tightness in flexion is noted, while the extension gap is felt to be balanced. Which of the following actions will effectively balance the knee? 1. Resect more distal femur. 2. Resect more anterior tibia. 3. Use a larger femoral component. 4. Use a smaller polyethylene insert. 5. Recess the posterior cruciate ligament.
PREFERRED RESPONSE: 5 DISCUSSION: Excessive flexion gap tightness can be addressed with a variety of techniques; including: (a) recess and release the posterior cruciate ligament; (b) resect a posterior slope in the tibia; (c) avoid an oversized femoral component that moves the posterior condyles more distally; (d) resect more posterior femoral condyle and use a smaller femoral component placed more anteriorly; and (e) release the tight posterior capsule and balance the collateral ligaments. REFERENCE Ayers DC, Dennis DA, Johanson NA, Pelligrini VD: Common complications of total knee arthroplasty. J Bone Joint Surg Am 1997;79:278-311.
Figures 2A and 2B show the current radiographs of a 58-year-old man who underwent total knee arthroplasty with a cruciate ligament-sparing prosthesis 7 years ago. Examination reveals boggy synovitis and moderate pain, particularly anteriorly. Management should consist of 1. follow-up radiographs. 2. alendronate, with follow-up examinations every 6 months. 3. revision to a posterior stabilized prosthesis. 4. exchange of the tibial insert through a limited incision. 5. surgical exploration with revision or exchange based on the findings.

PREFERRED RESPONSE: 5 DISCUSSION: The patient has symptoms of synovitis that are most likely the result of the release of particles from the tibial polyethylene. While observation may be warranted in a completely asymtomatic knee, some intervention is indicated for this patient as there is clear radiographic evidence of lysis in both the tibia and femur. The decision about the extent of the revision should be made at the time of surgery. A limited incision technique is not indicated. Grafting (or using graft substitute) the defect is the most appropriate approach for treating the osteolytic lesions. While a posterior stabilized prosthesis might be the solution, surgical findings might dictate otherwise. REFERENCE Brassard MF, Insall JN, Scuderi GR: Complications of total knee arthroplasty, in Insall JN, Scott WN (eds): Surgery of the Knee, ed 3. Philadelphia, PA, Churchill Livingstone, 2001, vol 2, pp 1801-1844.
What is the correct order of the elastic modulus of the following materials from greatest to least? 1. Stainless steel, cobalt-chromium, titanium, polymethylmethacrylate (PMMA), alumina ceramic 2. Cobalt-chromium, stainless steel, titanium, alumina ceramic, PMMA 3. Alumina ceramic, titanium, cobalt-chromium, stainless steel, PMMA 4. Alumina ceramic, cobalt-chromium, stainless steel, titanium, PMMA 5. Titanium, cobalt-chromium, alumina ceramic, stainless steel, PMMA
PREFERRED RESPONSE: 4 DISCUSSION: In Young’s modulus of elasticity, E is a measure of the stiffness of a material and its ability to resist deformation. In the elastic region of the stress-stain curve, E = stress/strain. The moduli of elasticity for these materials are alumina ceramic = 380 Gigapascals (GPa), cobalt-chromium = 210 GPa, stainless steel = 190 GPa, titanium = 116 GPa, and PMMA = 1.1 to 4.1 GPa. REFERENCES Buckwalter JA, Einhorn TA, Simon SR (eds): Orthopaedic Basic Science, ed 2. Rosemont, IL, American Academy of Orthopaedic Surgeons, 2000, pp 182-215.
Figure 3 shows the radiograph of a 75-year-old woman who reports the sudden onset of disabling medial knee pain. What is the most likely diagnosis? 1. Osteoarthritis 2. Osteonecrosis 3. Meniscal tear 4. Metastatic lesion 5. Synovial osteochondromatosis

PREFERRED RESPONSE: 2 DISCUSSION: Idiopathic osteonecrosis of the medial femoral condyle occurs predominantly in women older than age 60 years. It is characterized by pain centered in the medial anterior aspect of the knee, and onset is sudden. Flattening, sclerosis, and the radiolucent crescent sign are radiographic indicators of osteonecrosis. The radiographs show no narrowing of the joint space or osteophyte formation to indicate osteoarthritis, and there are no loose bodies to indicate synovial osteochondromatosis. A meniscal tear is not consistent with the radiographic findings shown here. Meniscal tears can coexist with osteonecrosis, but the pain is not eliminated merely by partial meniscectomy. Metastatic lesions to the distal femoral epiphysis are exceedingly rare. REFERENCES Urbaniak JR, Jones JP Jr (eds): Osteonecrosis: Etiology, Diagnosis, and Treatment. Rosemont, IL, American Academy of Orthopaedic Surgeons, 1997, pp 413-418. Insall JN, Windsor RE, Scott WN, Kelly MA, Aglietti P (eds): Surgery of the Knee, ed 2. New York, NY, Churchill Livingstone, 1993, pp 609-634.
When using highly cross-linked ultra-high molecular weight polyethylene as an articulating surface for total knee arthroplasty, what property of the material raises concern? 1. Decreased volumetric wear 2. Decreased ductility 3. Increased mobility of the ultra-high molecular weight polyethylene chains in the material 4. Increased fatigue resistance 5. Increased fracture toughness
PREFERRED RESPONSE: 2 DISCUSSION: The decreased mobility of the polymer chains from cross-linking leads to decreased volumetric wear but also to decreases in ductility and fatigue resistance. Stresses at the knee are higher and varied in the point of application, leading to the concern for fatigue resistance and fracture. REFERENCE Koval KJ (ed): Orthopaedic Knowledge Update 7. Rosemont, IL, American Academy of Orthopaedic Surgeons, 2002, pp 193-199.
An otherwise healthy 57-year-old man has persistent, severe hip pain after undergoing total hip arthroplasty 3 months ago. What is the next most appropriate step in management? 1. Serial radiographs to assess progressive radiolucency from osteolysis or mechanical loosening 2. Assessment of C-reactive protein, erythroctye sedimentation rate, and CBC, followed by aspiration 3. Technetium and/or indium-labeled leukocyte scintigraphy 4. A trial of broad-spectrum cefalosporin antibiotics to assess for a change in pain intensity 5. Injection with lidocaine and methylprednisolone acetate
PREFERRED RESPONSE: 2 DISCUSSION: Any patient who is severely symptomatic this quickly after surgery must be evaluated for infection. Loosening is also a possible cause, but infection must be ruled out. Bone scans are not helpful at this early postoperative stage. Normal laboratory values argue strongly against infection, but when abnormal, need to be supplemented with a hip aspiration. Aspiration remains the most selective and sensitive measure, especially when linked to a WBC count of the synovial tissues in the joint. There is no indication for an antibiotic trial because it may make future culture sensitivity more difficult. REFERENCES Drancourt M, Stein A, Argenson JN, et al: Oral rifampin plus ofloxacin for treatment of staphylococcus-infected orthopedic implants. Antimicrob Agents Chemother 1993;37:1214-1218. Duncan CP, Beauchamp C: A temporary antibiotic-loaded joint replacement system for the management of complex infections involving the hip. Orthop Clin North Am 1993;24:751-759. Oyen WJ, Claessens RA, van Horn JR, et al: Scintiographic detection of bone and joint infections with indium-111-labeled nonspecifonal human immunoglobulin G. J Nucl Med 1990;31:403-412.
Which of the following treatments of polyethylene results in the highest amount of oxidative degradation? 1. Ethylene oxide sterilization 2. Gamma irradiation in air 3. Gamma irradiation in an inert environment 4. Gamma irradiation followed by cross-linking 5. Gas plasma sterilization
PREFERRED RESPONSE: 2 DISCUSSION: Oxidative degradation of polyethylene occurs as a function of time in an air environment. In an environment such as argon, nitrogen, or a vacuum, the process is reduced. Ethylene oxide is an alternative for sterilization in which the cross-link degradation is minimized because of the absence of oxidative interactions. Gamma sterilization or use of ethylene oxide gas is the industry standard; however, oxygen concentrations are now reduced to a minimal level to retard the oxidation phenomenon. REFERENCES Sanford WM, Saum KA: Accelerated oxidative aging testing of UHMWPE. Trans Orthop Res Soc 1995;20:119. Sun DC, Schmidig G, Stark C, et al: On the origins of a subsurface oxidation maximum and its relationship to the performance of UHMWPE implants. Trans Soc Biomater 1995;18:362. Callaghan JJ, Dennis DA, Paprosky WA, Rosenberg AG (eds): Orthopaedic Knowledge Update: Hip and Knee Reconstruction. Rosemont, IL, American Academy of Orthopaedic Surgeons, 1995, pp 35-41. McKellop HA: Bearing surfaces in total hip replacement: State of the art and future developments. Instr Course Lect 2001;50:165-179.
Consider the theoretic articulation shown in Figure 4 as femoral and tibial components of a total knee prosthesis in which the components fit like a “roller in trough.” Which of the following best describes the articulation? 1. Constrained to anteroposterior translation, unconstrained to medial-lateral translation, high contact stress on edge (ie, varus-valgus) loading 2. Constrained to anteroposterior translation, unconstrained to medial-lateral translation, low contact stress on edge (ie, varus-valgus) loading 3. Unconstrained to anteroposterior translation, constrained to medial-lateral translation, high contact stress on edge (ie, varus-valgus) loading 4. Unconstrained to anteroposterior translation, constrained to medial-lateral translation, low contact stress on edge (ie, varus-valgus) loading 5. Constraint is dependent on the status of the posterior cruciate ligament

PREFERRED RESPONSE: 1 DISCUSSION: The theoretic total knee components will resist anteroposterior motion by making the femoral component “climb the walls” of the tibial component. As drawn, there is no constraint to medial-lateral translation. The cylinder is not rounded on the edges, so varus-valgus motion will impart load from the cylinder to the trough over a small area, thus having a high contact stress. REFERENCE Alicea J: Scoring systems and their validation for the arthritic knee, in Insall JN, Scott WN (eds): Surgery of the Knee, ed 3. Philadelphia, PA, Churchill Livingstone, 2001, vol 2, pp 1507-1515.
Wear particles of ultra-high molecular weight polyethylene that are generated by total hip implants are predominantly of what diameter? 1. Less than 1 micron 2. 10 to 50 microns 3. 100 to 200 microns 4. 500 to 750 microns 5. Greater than 1,000 microns
PREFERRED RESPONSE: 1 DISCUSSION: Multiple studies have shown that the size of an ultra-high molecular weight polyethylene particle generated by total hip implants is typically less than 1 micron. This finding is significant in that particles of that size are readily phagocytized by macrophages. REFERENCES Campbell P, Ma S, Yeom B, McKellop H, Schmalzried TP, Amstutz HC: Isolation of predominantly submicron-sized UHMWPE wear particles from periprosthetic tissues. J Biomed Mater Res 1995;29:127-131. Shanbhag AS, Jacobs JJ, Glant TT, Gilbert JL, Black J, Galante JO: Composition and morphology of wear debris in failed uncemented total hip replacement. J Bone Joint Surg Br 1994;76:60-67. Maloney WJ, Smith RL, Schmalzried TP, Chiba J, Huene D, Rubash H: Isolation and characterization of wear particles generated in patients who have had failure of a hip arthroplasty without cement. J Bone Joint Surg Am 1995;77:1301-1310.
Which of the following best describes the resultant forces on an increased offset stem when compared with a standard offset stem? 1. Increased joint reaction force, increased torsional load 2. Increased joint reaction force, decreased torsional load 3. Decreased joint reaction force, increased torsional load 4. Decreased joint reaction force, decreased torsional load 5. No change in joint reaction force or torsional load
PREFERRED RESPONSE: 3 DISCUSSION: The increased emphasis on restoring offset in total hip arthroplasty has implications for the forces applied to the components and the fixation interfaces. Static analysis has shown that with an increased affect, joint reaction force on the articulation is decreased. When the resultant load on the hip is “out of plane” (ie, directed anterior to posterior), there is increased torsion where the stem is turned into more retroversion. REFERENCES Buckwalter JA, Einhorn TA, Simon SR (eds): Orthopaedic Basic Science, ed 2. Rosemont, IL, American Academy of Orthopaedic Surgeons, 2000, pp 134-180. Hurwitz DE, Andriaacchi TP: Biomechanics of the hip, in Callaghan J, Rosenberg AG, Rubash HE (eds): The Adult Hip. Philadelphia, PA, Lippincott-Raven, 1998. Pauwels F: Biomechanics of the Normal and Diseased Hip. New York, NY, Springer-Verlag, 1976.
During total knee arthroplasty, what component position aids in proper tracking and stability of the patellar component? 1. Femoral component in external rotation 2. Tibial component in internal rotation 3. Medialization of the tibial tray 4. Lateralization of the patellar component 5. Medialization of the femoral component
PREFERRED RESPONSE: 1 DISCUSSION: The femoral component should be implanted with enough external rotation to facilitate patellar tracking. Proper tracking requires a normal Q angle and is affected by axial and rotational alignment of the femur and tibia. An excessive Q angle can result from internal rotation of either component, medialization of the tibial tray, or lateralization of the patellar component. REFERENCES Beaty JH (ed): Orthopaedic Knowledge Update 6. Rosemont, IL, American Academy of Orthopaedic Surgeons, 1999, pp 559-582. Lonner JH, Lotke PA: Aseptic complications after total knee arthroplasty. J Am Acad Orthop Surg 1999;7:311-324.
A 60-year-old woman reports anterior knee pain 2 years after undergoing primary total knee arthroplasty for rheumatoid arthritis. A Merchant view of the patella is shown in Figure 5. What is the most likely cause of her pain? 1. Elevation of the joint line 2. Lateral placement of the femoral component 3. Medial placement of the patellar component 4. Internal rotation of the femoral component 5. External rotation of the tibial component

PREFERRED RESPONSE: 4 DISCUSSION: Patellar complications commonly occur after primary total knee arthroplasty; therefore, proper component positioning is critical in obtaining a successful result. This patient has lateral tilting and subluxation of the patellar component. Internal rotation of the femoral component has the most deleterious effect on patellar tracking. Lateral placement of the femoral component, medial placement of the patellar component, and external rotation of the tibial component have beneficial effects on patellar tracking. Elevation of the joint line, if not excessive, should not impact patellar tracking. REFERENCES Rand JA: Patellar resurfacing in total knee arthroplasty. Clin Orthop Relat Res 1990;260:110-117. Healy WL, Wasliewski SA, Takei R, Oberlander M: Patellofemoral complications following total knee arthroplasty: Correlation with implant design and patient risk factors. J Arthroplasty 1995;10:197-201.
The anterior portal of a hip arthroscopy places what structure at greatest risk for injury? 1. Ascending branch of the lateral circumflex femoral artery 2. Ascending branch of the medial circumflex femoral artery 3. Femoral nerve 4. Lateral femoral cutaneous nerve 5. Superior gluteal nerve
PREFERRED RESPONSE: 4 DISCUSSION: The average location of the anterior portal is 6.3 cm distal to the anterior superior iliac spine. The lateral femoral cutaneous nerve typically has divided into three or more branches at the level of the anterior portal. The portal usually passes within several millimeters of the most medial branch. Injury to the nerve can lead to meralgia paresthetica. The femoral nerve lies an average minimum distance of 3.2 cm from the anterior portal. The ascending branch of the lateral circumflex artery lies approximately 3.7 cm inferior to the anterior portal. Neither the ascending branch of the medial circumflex artery nor the superior gluteal nerve are at risk. REFERENCES Byrd JWT: Operative Hip Arthroscopy. New York, NY, Thieme Medical Publishers, 1998, pp 83-91. Arendt EA (ed): Orthopaedic Knowledge Update: Sports Medicine 2. Rosemont, IL, American Academy of Orthopaedic Surgeons, 1999, pp 281-289.
A 32-year-old man has posttraumatic arthritis after undergoing open reduction and internal fixation of a left acetabular fracture. A total hip arthroplasty is performed, and the radiograph is shown in Figure 6. What is the most common mode of failure leading to revision in this group of patients? 1. Infection 2. Heterotopic ossification 3. Dislocation 4. Periprosthetic fracture 5. Acetabular component loosening

PREFERRED RESPONSE: 5 DISCUSSION: Acetabular component loosening has been reported as the most common mode of failure following total hip arthroplasty in patients with a previous acetabular fracture. Following acetabular fracture and subsequent open reduction and internal fixation, the bone quality and vascularity are compromised, thus reducing the success rate of acetabular component cementless fixation. REFERENCES Jimenez ML, Tile M, Schenk RS: Total hip replacement after acetabular fracture. Orthop Clin 1997;28:435-446. Romness DW, Lewallen DG: Total hip arthroplasty after fracture of the acetabulum: Long-term results. J Bone Joint Surg Br 1990;72:761-764.
A 42-year-old man sustained the periprosthetic fracture shown in Figures 7A and 7B. The femoral component is well fixed. What is the next most appropriate step in management? 1. Closed reduction and bracing 2. Retrograde femoral intramedullary nailing 3. Open reduction and internal fixation of the fracture, leaving the femoral stem in place 4. Open reduction and internal fixation of the fracture and insertion of a proximally porous-coated stem 5. Open reduction and internal fixation of fracture fragments and insertion of a fully porous-coated femoral stem with diaphyseal fixation distal to the fracture

PREFERRED RESPONSE: 3 DISCUSSION: The patient has a periprosthetic fracture below the femoral stem. The component is porous coated and well fixed. Open reduction and internal fixation, leaving the stem in place, can be performed when bone quality is good. Plating with or without allograft struts and supplemental cerclage fixation generally is acceptable. If the component is loose, revision to a longer device is recommended with appropriate stabilization of the fracture using the aforementioned methods. If bone loss has occurred, allograft supplementation or a tumor prosthesis may be indicated. Fractures located well below the stem tip can be treated without regard for the prosthesis. Closed reduction and bracing is not associated with good results for periprosthetic femoral fractures. Retrograde intramedullary nailing is not appropriate for this fracture. REFERENCES Duncan CP, Masri BA: Fractures of the femur after hip replacement. Instr Course Lect 1995;44:293-304. Bono JV, McCarthy JC, Thornhill TS, Bierbaum BE, Turner RH (eds): Revision Total Hip Arthroplasty. New York, NY, Springer Verlag, 1999, pp 530-592.
A homebound 75-year-old woman with diabetes mellitus has had progressive left knee pain and swelling for the past 6 weeks. She is febrile with a temperature of 103°F (39.5°C). History reveals that she underwent arthroplasty 5 years ago. Examination shows passive range of motion of 0° to 100° with no active extension. Knee aspiration reveals purulent fluid with a Gram stain showing gram-negative rods. A radiograph is shown in Figure 8. In addition to IV antibiotics, which of the following management options offers the best chance of a successful outcome? 1. Incision and drainage with repair of the extensor mechanism 2. Removal of components and delayed revision knee arthroplasty with an allograft extensor mechanism 3. Removal of components and immediate exchange revision total knee arthroplasty 4. Removal of components and delayed knee arthrodesis 5. Removal of components and delayed revision knee arthroplasty with extensor mechanism repair

PREFERRED RESPONSE: 4 DISCUSSION: The patient has an infected total knee arthroplasty and an interrupted extensor mechanism. A late infection of a total knee arthroplasty in a patient with diabetes mellitus and a virulent organism requires removal of the components, debridement, antibiotic spacers, and surveillance to ensure eradication of the infection. Reconstruction of an incompetent extensor mechanism in an infected knee is extremely unlikely to be successful. Arthrodesis is the procedure of choice if a revision total knee arthroplasty is not likely to succeed. Resection arthroplasty is recommended only as a long-term solution if the patient is medically unable to undergo further surgery. REFERENCES Koval KJ (ed): Orthopaedic Knowledge Update 7. Rosemont, IL, American Academy of Orthopaedic Surgery, 2002, pp 513-536. Hanssen AD, Rand JA: Evaluation and treatment of infection at the site of a total hip or knee arthroplasty. Instr Course Lect 1999;48:111-122.
Varus intertrochanteric osteotomy for coxa valga commonly produces which of the following results? 1. Decreased abductor lever arm 2. Increased hip joint reaction force 3. Increased center edge angle 4. Abductor lag and lurch 5. Lengthening of the leg
PREFERRED RESPONSE: 4 DISCUSSION: The greater trochanter is raised as a by-product of varus osteotomy, and a temporary abductor lag and lurch is common for 6 months following surgery. In the absence of hip joint subluxation, varus intertrochanteric osteotomy has no effect on the center edge angle of Wiberg. Varus osteotomy typically increases femoral offset, thereby improving the abductor lever arm and reducing the hip joint reaction force. Even without taking a wedge, varus osteotomy always produces some degree of shortening. REFERENCE Millis MB, Murphy SB, Poss R: Osteotomies about the hip for the prevention and treatment of osteoarthrosis. Instr Course Lect 1996;45:209-226.
During a posterior cruciate ligament-sacrificing total knee arthroplasty with anterior referencing, 8 mm of distal femur is resected. It is noted that the flexion gap is tight and the extension gap appears stable. What is the next most appropriate step in management? 1. Cut more proximal tibia. 2. Cut more distal femur. 3. Cut both the proximal tibia and distal femur. 4. Decrease the size of the femoral component. 5. Decrease the tibial polyethylene insert thickness.
PREFERRED RESPONSE: 4 DISCUSSION: If the flexion gap is tight and the extension gap is correct, it is preferable to change only the flexion gap and leave the extension gap unchanged; therefore, the treatment of choice is to decrease the size of the femoral component. The smaller component will be smaller in both medial-lateral as well as anterior-posterior dimensions. A smaller anterior-posterior size will allow more space for the flexion gap without significantly affecting the extension gap. Decreasing the size of the tibial polyethylene insert thickness or cutting more proximal tibia will affect both the flexion and extension gaps. Cutting more distal femur will increase the extension gap and not change the flexion gap, making the described situation worse. Cutting both the proximal tibia and distal femur will increase both the flexion and extension gaps. REFERENCE Pellicci PM, Tria AJ Jr, Garvin KL (eds): Orthopaedic Knowledge Update: Hip and Knee Reconstruction 2. Rosemont, IL, American Academy of Orthopaedic Surgeons, 2000, pp 281-286, 339-365.
A 58-year-old man has anterior knee pain after undergoing total knee arthroplasty for osteoarthritis 2 years ago. He denies any history of trauma. A Merchant view is shown in Figure 9. What is the most likely cause of his pain? 1. External rotation of the femoral component 2. Overstuffing of the patellofemoral joint 3. Less than 12 mm of bony patella remaining after resection 4. Lateral retinacular release 5. Use of a cemented patellar component

PREFERRED RESPONSE: 3 DISCUSSION: The patient has a patellar stress fracture after resurfacing in a total knee arthroplasty. Several studies have shown that over-resection of the patella to less than 12 to 15 mm increases anterior patellar surface strains to a point where the risk of fracture is increased. Increasing the patellar thickness, positioning of the femoral component, lateral releases, and component types have not been clearly associated with increased fracture risk. REFERENCES Reuben JD, McDonald CL, Woodard PL, Hennington LJ: Effect of patella thickness on patella strain following total knee arthroplasty. J Arthroplasty 1991;6:251-258. Hsu HC, Luo ZP, Rand JA, An KN: Influence of patellar thickness on patellar tracking and patellofemoral contact characteristics after total knee arthroplasty. J Arthroplasty 1996;11:69-80. Greenfield MA, Insall JN, Case GC, Kelly MA: Instrumentation of the patellar osteotomy in total knee arthroplasty: The relationship of patellar thickness and lateral retinacular release. Am J Knee Surg 1996;9:129-131.
Etanercept is a recombinant genetically engineered fusion protein used to treat rheumatoid arthritis. What is its mode of action? 1. Monoclonal antibody that binds TNF-α 2. Blocks the binding of IL-1 to receptors 3. Soluble receptor that binds TNF-α 4. Soluble factor that binds rheumatoid factor 5. Directly inhibits pyrimidine synthesis
PREFERRED RESPONSE: 3 DISCUSSION: Etanercept is a molecule consisting of the Fc portion of IgG fused to the extracellular domain of the p76 human THF-α receptor. It is soluble and binds TNF-α. Infliximab is the monoclonal antibody that binds TNF-α. IL-1 receptor antagonists are still in development. Leflunomide is a drug that inhibits pyrimidine synthesis and is similar to methotrexate as an antimetabolite. REFERENCE Koval KJ (ed): Orthopaedic Knowlegde Update 7. Rosemont, IL, American Academy of Orthopaedic Surgeons, 2002, pp 193-199.











