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Pharmacology Exam 3 > 2009 Exam > Flashcards

2009 Exam Flashcards

1
Q

Class IV antiarrhythmic drugs

A. Increase the PR interval on the ECG

B. prolong the ventricular action potential

C. act on G-protein coupled receptor

D. include nifedipine (Procardia)

A

A

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2
Q

Amiodarone (Cordarone)

A. has relatively few side effects

B. decreases the QT interval on the ECG

C. blocks K+ channels

D. is a Class I antiarrhythmic drug

A

C

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3
Q

Class IC antiarrhythmic drugs

A. include lidocaine (Xylocaine)

B. should not be given to pts with myocardial infarction

C. are administered intravenously

D. cannot be used to treat supraventricular arrhythmias

A

B

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4
Q

Arrhythmias due to re-entry

A. can be treated with adenosine (Adenocard)

B. may result form myocardial infarction

C. result from improper conduction of action potential

D. All of the above

A

D. all of the above

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5
Q

Alteplase (Activase)

A. is a recombinant human tissue-type plasminogen activator (t-PA)

B. selectively degrades fibrin A and B

C. Both A and B

D. Neither A nor B

A

C. Both A and B

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6
Q

Which of the following mechanisms do NOT contribute to the beneficial effects of ACE inhibitors when they are used for the treatment of heart failure?

A. reduced preload

B. reduced afterolad

C. Increased intracellular Ca concentration in cardiac myocytes

D. increased renal Na retention

A

C

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7
Q

Digitalis glycosides

A. have a wide margin of safety

B. Increase the intracellular free Ca concentration in cardica myocytes

C. are characterized by both A and B

D. neither A nor B

A

B

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8
Q

When used for the treatment of angina pectoris, which of the following statements about organic nitrates is FALSE?

a. they reduce preload

B. they markedly dilate myocardial coronary arterioles in the ischemic zone

C. they inhibit platelet aggregation

D. they are degraded to the vasodilator gas nitic oxide

A

B

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9
Q
A
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10
Q

cortisol

A. is a long acting glucocorticoid

B. has minimal salt-retaining activity

C. both

D. neither

A

D

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11
Q

which of the following is TRUE about glucocorticoids?

A. decrease expression of lipocortin

B. abrupt withdrawal can lead to acute adrenal insufficiency

C. All glucocorticoids bind with high affinity to the aldosterone receptor

D. no adverse effects are ever associated with long term use

A

B

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12
Q

Which of the following drugs blocks the synthesis of ALL eicosanoids?

A. acetaminophen (tylenol)

B. ibuprofen (motrin)

C. prednisone (deltasone)

D. celecoxib (celebrex)

E. none

A

C

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13
Q

increases the excretion of uric acid in treatment of gout

A. indomethacin (indocin)

B. methotrexate (MTX)

C. Allopurinol (Zyloprim)

D. Anakinra (kineret)

E. probenecid (benemid)

A

E

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14
Q

is the drug of choice for the treatment of most RA through inhibition of dihydrofolate reductase

A. indomethacin (indocin)
B. methotrexate (MTX)

C. Allopurinol (Zyloprim)
D. Anakinra (kineret)

E. probenecid (benemid)

A

B

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15
Q

antagonizes the action of IL-1 from the treatment of RA

A. indomethacin (indocin)
B. methotrexate (MTX)

C. Allopurinol (Zyloprim)
D. Anakinra (kineret)

E. probenecid (benemid)

A

D

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16
Q

provides rapid relief from acute gouty arthritis attacks

A. indomethacin (indocin)
B. methotrexate (MTX)

C. Allopurinol (Zyloprim)
D. Anakinra (kineret)

E. probenecid (benemid)

A

A

17
Q

an antagonist of muscarinic cholinergic receptors and is especilly useful in treating patients with nocturnal and exercise induced asthma

A. ipratropium (atrovent)

B. salmetrol (serevent)

C. albuterol (provent)

D. corticosteroid (fluticasone)

A

A

18
Q

is a short-acting agonist selective for beta-2 adrenergic receptors and functions as a bronchodilator

A. ipratropium (atrovent)

B. salmetrol (serevent)

C. albuterol (provent)

D. corticosteroid (fluticasone)

A

C

19
Q

is a long-acting agonist of beta-2 adrenergic receptors; rare episodes of asthma symptom exacerbations have raised cautions over its use

A. ipratropium (atrovent)

B. salmetrol (serevent)

C. albuterol (provent)

D. corticosteroid (fluticasone)

A

B

20
Q

T or F: acetaminophen is not useful for treating anti-inflammatory responses

A

True

21
Q

montelukast Na (singulair) is useful for treating gastric ulcers that result from chronic use of non-steroidal anti-inflammatory drugs (NSAIDs)

A

False

Pharmacology Exam 3 (8 decks)

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