20 - Respiratory Failure Flashcards
Concentration of oxygen in air
20.94%
Barometric pressure (atmospheric pressure)
101.3kpa
PO2 of dry air at sea level
21.2kpa
o2 in air x atmospheric pressure
What is tracheal gas
PO2 after humidification
How to work out tracheal gas
• Fractional concentration of oxygen in the dry gas phase x (barometric pressure - SVP) FiO2 x (PB - SVP)
What effects alveolar PO2
Ventilation
O2 consumption/CO2 production
Alveolar PaO2
dry barometric pressure x (FiO2-VO2 / VA)
What is FiO2, VO2 and Va
o FiO2 – inspired oxygen concentration- 21/20.93
o VO2- oxygen consumption(round 250 ml/min)
o VA- alveolar ventilation
What is the alveolar to arterial PO2 difference determined by
Shunting
What is the normal A-A O2 difference
not normally greater than 2 kPa
What is shunting
An area of the lung that is perfused but not ventilated
Has blood supply but not oxygen
What is oxygen delviery
= [Hb] x Oxygen Saturation of Hb x 1.34 x 10 x Cardiac Output
o Round 1 litre per minute
Signs of respiratory compensation
Tachypnoea > 20
Use of accessory muscles
Nasal flaring
Signs of increased sympathetic tone
Tachycardia
Hypertension
Sweating
Signs of end-organ hypoxia
Altered mental status
Bradycardia and hypotension