2. Vasodilators Flashcards
Which calcium channel blocker has the greatest effect on L type calcium channels in the heart?
verapamil
Which phase of depolarization do calcium channel blockers inhibit in the SA and AV nodes?
phase 0
Calcium channel blockers inhibit which stage of depolarization in regular atrial and ventricular tissue?
phase 2 (plateau)
Which class of calcium channel blockers can cause an INCREASE in heart rate?
DHPs (amlodipine)
Which CC blocker can be used in supraventricular tachyarrhythmia?
verapamil
Which CC blocker should not be combined with digoxin?
verapamil
Which vasodilator can lead to hypersensitivity due to sodium metabisulfite formation?
fenoldopam
Which calcium channel blocker has the greatest effect on L type calcium channels in the heart?
verapamil
Which phase of depolarization do calcium channel blockers inhibit in the SA and AV nodes?
phase 0
Calcium channel blockers inhibit which stage of depolarization in regular atrial and ventricular tissue?
phase 2 (plateau)
Which class of calcium channel blockers can cause an INCREASE in heart rate?
DHPs (amlodipine)
Which CC blocker should not be combined with digoxin?
verapamil
What is another indication for minoxidil (besides hair growth)?
HTN refractory to treatment
Which vasodilator carries a risk of cardiac tamponade?
minoxidil
Which vasodilator can lead to hypersensitivity due to sodium metabisulfite formation?
fenoldopam
What is the direct effect of calcium channel blockers in blood vessels?
dec. influx through L type calcium channels
arteriodilation, dec TPR
What is the vascular effect of minoxidil?
arteriodilators
Which vasodilator can cause cyanide toxicity?
nitroprusside
What is the vascular effect of nitroprusside?
equal arterio- and venodilation
What is the main vascular effect of organic nitrates?
venodilation
