2. Vasodilators Flashcards

1
Q

Which calcium channel blocker has the greatest effect on L type calcium channels in the heart?

A

verapamil

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2
Q

Which phase of depolarization do calcium channel blockers inhibit in the SA and AV nodes?

A

phase 0

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3
Q

Calcium channel blockers inhibit which stage of depolarization in regular atrial and ventricular tissue?

A

phase 2 (plateau)

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4
Q

Which class of calcium channel blockers can cause an INCREASE in heart rate?

A

DHPs (amlodipine)

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5
Q

Which CC blocker can be used in supraventricular tachyarrhythmia?

A

verapamil

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6
Q

Which CC blocker should not be combined with digoxin?

A

verapamil

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7
Q

Which vasodilator can lead to hypersensitivity due to sodium metabisulfite formation?

A

fenoldopam

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8
Q

Which calcium channel blocker has the greatest effect on L type calcium channels in the heart?

A

verapamil

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9
Q

Which phase of depolarization do calcium channel blockers inhibit in the SA and AV nodes?

A

phase 0

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10
Q

Calcium channel blockers inhibit which stage of depolarization in regular atrial and ventricular tissue?

A

phase 2 (plateau)

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11
Q

Which class of calcium channel blockers can cause an INCREASE in heart rate?

A

DHPs (amlodipine)

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12
Q

Which CC blocker should not be combined with digoxin?

A

verapamil

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13
Q

What is another indication for minoxidil (besides hair growth)?

A

HTN refractory to treatment

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14
Q

Which vasodilator carries a risk of cardiac tamponade?

A

minoxidil

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15
Q

Which vasodilator can lead to hypersensitivity due to sodium metabisulfite formation?

A

fenoldopam

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16
Q

What is the direct effect of calcium channel blockers in blood vessels?

A

dec. influx through L type calcium channels

arteriodilation, dec TPR

17
Q

What is the vascular effect of minoxidil?

A

arteriodilators

17
Q

Which vasodilator can cause cyanide toxicity?

A

nitroprusside

17
Q

What is the vascular effect of nitroprusside?

A

equal arterio- and venodilation

17
Q

What is the main vascular effect of organic nitrates?

A

venodilation