2. sepsis

Question 1

what are the criteria for SIRS (systemic inflammatory response syndrome)

Answer 1

temp outside the range of 36-38
HR > 90
RR > 20
WBC count outside the range of 4,000 - 20,000

Question 2

what antimicrobial therapy is FIRST given for a sepsis of unknown origin

Answer 2

co-amoxiclav + gentamicin (add vancomycin if MRSA)

Question 3

what antimicrobial therapy is typically used in hospital acquired infections

Answer 3

gentamicin + piperacillin-tazobactum (tazocin)

Question 4

what antimicrobial therapy is added if MRSA is suspected

Answer 4

vancomycin

Question 5

what is the sepsis six?

Answer 5

• high flow o2
• take blood cultures
• give broad spectrum antibiotics
• give IV fluids
• measure serum LACTATE and HB
• measure hourly urine output