2: Renal-Tubular Acidosis Flashcards
1
Q
What ABG abnormality do all types of RTA cause
A
- Normal anion gap metabolic acidosis
- High chloride ions
2
Q
What is type I RTA
A
Unable to secrete H+ in distal tubule
3
Q
What electrolyte abnormality does RTA I cause
A
K+
4
Q
What are complications of RTA type I
A
- Renal stones
5
Q
What causes RTA type I
A
- SLE
- Sjogrens
- RA
- Analgesic nephropathy
6
Q
What is type II RTA
A
Unable to re-absorb HCO3- in PCT
7
Q
What electrolyte abnormality does type II RTA cause
A
Hypokalaemia
8
Q
What is a complication of type II RTA
A
- Osteomalacia
9
Q
What causes type II RTA
A
- Fanconi
- Wilson
- Tetracyclines
- Carbonic anhydrase inhibitors
10
Q
What causes type 4 RTA
A
reduction in aldosterone leads to reduction in proximal tubular ammonium excretion
11
Q
what electrolyte abnormality is there in type 4
A
hyperkalaemia
12
Q
what causes type 4 RTA
A
Addisons
diabetes