1: Acid-Base Balance Flashcards
What are the 4 main acid-base balance disorders
- Respiratory acidosis
- Respiratory alkalosis
- Metabolic acidosis
- Metabolic alkalosis
What causes respiratory acidosis
Alveolar Hypoventilation
How can causes of respiratory acidosis be divided
- Pulmonary Disease
2. NM Disease
What are 4 pulmonary causes of respiratory acidosis
- COPD
- Pneumonia
- Fibrosis
- OSA
What are 5 neuromuscular disorders leading to respiratory acidosis
- CNS Tumour
- CNS Trauma
- Myasthenia gravis
- Gullian barre
- MND
- Poliomyelitis
- Cervical cord lesion
What in-general causes respiratory alkalosis
alveolar hyperventilation.
what may cause alveolar hyperventilation
anxiety
salicylate OD
high altitude
mechanical ventilation
What are the two broad causes of metabolic acidosis
- Increase H+ production
- Decrease HCO3- production
What type of metabolic acidosis does increase production of H+ cause
Metabolic acidosis with raised anion gap
What type of metabolic acidosis does decrease HCO3- cause
Metabolic acidosis with normal anion gap
What are the two broad causes of metabolic alkalosis
- Loss H+
- Excess HCO3-
What are 3 causes of metabolic alkalosis
Burns
Potassium-loss (Thiazide, Loop Diuretics
Vomiting
What is first-looked at in ABG
Oxygen
What defines hypoxia
Oxygen less-than 8
What should be remembered when looking at oxygen in ABG
FIO2
What is next looked at in ABG after oxygen
Carbon Dioxide
What is reference range for carbon dioxide
4.5-6.0
What is reference range for pH
7.35-7.45
What is reference range for HCO3-
22-28
What should be calculated if a person has a metabolic acidosis
Anion gap
What is the calculation for anion gap
(Na + K) - (Cl + HCO3)
What is a normal anion gap
10-18
What is a mnemonic to remember causes of metabolic acidosis with raised anion gap
MUDPILES
What are the causes of metabolic acidosis with raised anion gap
Methanol Urea DKA Paraldehyde Isoniazid, Iron Lactate Ethylene glycol Salicylate
What is a mnemonic to remember causes of metabolic acidosis with normal anion gap
FUSECARDS
What are the causes of metabolic acidosis with normal anion gap
Fistula pancreas Ureto-gastric conduit Saline Endocrine. Addison's disease Carbonic anhydrase inhibitor Ammonium chloride Renal tubular acidosis Diarrhoea Spironolactone
What may be given in metabolic acidosis if pH is less than 7.1
Sodium Bicarbonate