2. Microbiology and Smoking Flashcards

1
Q

What papillae are present in the tongue

A
  1. Filiform
  2. Fungiform
  3. Foliate
  4. Circumvellate
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2
Q

What antibodies in GCF

A

IgA

IgG

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3
Q

What evidence supports the bacterial aetilogy of periodontal disease

A
  1. Clinical Observation
  2. Perio Dx in germ free animals
    3, Observation of monoinfected animals
  3. Experimental disease in animals and humans
  4. Plaque control in humans
  5. Epidemiological Studies
  6. Pathogenic potential of bacterial plaque
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4
Q

Discuss Loe’s work in 1965

A

Plaque causes gingivitis
14 - 21 days to occur
Resolves with OH

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5
Q

Discuss the non specific plaque hypothesis

A

The bacterial community causes the disease

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6
Q

Discuss the specific plaque hypothesis

A

Certain bacteria cause the disease

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7
Q

What is the bacterial flora in health

A

Gram + non motile streptococci

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8
Q

What is the bacterial flora in gingivitis

A

Gram + rods eg A Viscous

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9
Q

What is the bacterial flora in perio dx

A

Gram Negative
Increasing motility
S Sanguis, F Nucleatum

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10
Q

Bacterial Flora in ANUG

A

Spirochete - T Pallidium

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11
Q

Bacterial Flora in ANUP

A

50% are uncultivable

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12
Q

What bacterial flora in abscess

A

Gram - rods

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13
Q

What are the red complex bacteria

A
  1. T Forsythia
  2. T Denticola
  3. P Gingivalis
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14
Q

What are the virulence factor of A Actino

A
  1. Polysaccharide / LDS
  2. Leukotoxin
  3. Extracellular proteins
  4. GroEl heat shock protein
  5. Fimbriae
  6. Other membrane proteins
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15
Q

What are the bacterial flora in T Denticola

A
  1. LPS
  2. Flagellum
  3. Extracellular Proteolytic Enzyme
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16
Q

What are the bacterial flora in T Forsythia

A
  1. LPS

2. Extracellular proteolytic enzymes

17
Q

What are the bacterial flora in P Gingivalis

A
  1. Capsule
  2. LPS
  3. Fimbriae
  4. GroEl heat shock proteins
  5. Haemaglutin’s
18
Q

Smoking is a systemic risk factor for what

A
  1. COPD
  2. MI
  3. Stroke
  4. CVD
  5. Cancer
19
Q

What study identifies smoking as a risk factor

A

Grossi

20
Q

How does smoking increase risk for perio dx

A
Toxins
Immunosuppression
Increased bacterial adhesion
Reduced oxygen tension
Vasoconstriction
Increased cytokines
Reduced fibroblast proliferation

CONFIT BV

21
Q

What effect does smoking have on Non Surgical trt

A

Increased residual pocket
Less reduction in PD
Reduced wound healing
Less pathogen reduction

22
Q

What effect does smoking have on surgical treatment

A
Reduces wound healing
Reduces grafting success
Reduced CAL
Reduced PD reduction
Reduced root coverage
23
Q

What effect does smoking have on impl success

A

No difference

24
Q

What effect does smoking have on maintenance and retreatment

A

Reduced success
Increased refractory
Graded response

25
Q

What are the 5 A’s of smoking cessation

A
  1. Ask
  2. Advise
  3. Assist
  4. Arrange
  5. Assess
26
Q

Why do Koch postulates not apply

A

Can’t grow some bacteria in media

27
Q

What are Kochs Postulates

A
  1. Organism found in the lesion
  2. Must be isolated and grown in culture on artificial media
  3. Inoculation causes similar lesions
  4. Micro Organism isolated from the lesion
28
Q

What are the alternatives to Kochs postulates

A
  1. Assoc with the disease
  2. Elimination of the organism
  3. Host Response
  4. Animal pathogenicity
  5. Mechanism of pathogenicity
29
Q

How does P Ginigvalis cause increased clotting

A

Proteolytic enzymes produced by P Ging activate prothrombin

30
Q

What does CRP do and why is it important

A

Binds to damaged cells, fixes compliment and activates neutorphil chemotaxis