2: Lecture 1 Summary

Question 1

What effects Heart and how

Answer 1

What: Beta blockers, peripherally acting sympathoplegics
How: Decrease force of contractility and heart rate
Overall: Blood pressure is decrease via a decrease in cardiac output

Question 2

What effects Kidneys and how

Answer 2

What: Diuretics, ACE inhibitors, beta blockers
How: Decrease blood volume
Overall: Blood pressure is decrease via a decrease in cardiac output

Question 3

What effects Smooth muscle (peripheral blood vessels) and how

Answer 3

What: peripherally acting sympathoplegics, Ca2+ channel blockers, oral vasodilators, ACE inhibitors
How: relax vascular smooth muscle
Overall: Blood pressure is decreased via a decrease in total peripheral resistance

Question 4

What effects CNS and how

Answer 4

What: Centrally acting sympathoplegics, beta-blockers
How: decrease sympathetic outflow
Overall: Blood pressure is decrease via a decrease is cardiac output and total peripheral resistance