2. Infection Symposium - Severe Odontogenic Infection & Sepsis

Question 1

Define Ludwig’s angina.

Answer 1

Bilateral infection of submandibular space.

Question 2

What are the 4 microorganisms associated with Ludwig’s angina ?

Answer 2

P. intermedia.
S. anginosus.
Anaerobic streptococci.
S. aureus.

Question 3

What toxin does S. Aureus produce ?

Answer 3

Panton-valentine leukocidin toxin.

Question 4

S. Aureus - what is the function of Panto-Valentine Leukocidin ?

Answer 4

Destructive of WBCs.

Question 5

Define sepsis.

Answer 5

Systemic inflammatory response syndrome (SIRS) + suspected/confirmed infection.

Life threatening organ dysfunction caused by dysregulated host response to infection.

Question 6

What are the four components to diagnosis of sepsis (indicative SIRS) ?

Answer 6

Temperature <36 or >38 degrees.
Pulse >90/min.
Respiratory rate >20/min.
WCC <4 or >12.