13. Oral Cancer (OMFS) Flashcards

1
Q

What is the prognosis for HNC ?

A

50%

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2
Q

What is the main aetiological factors for cancer of the mouth ?

A

Local carcinogens - smoking, alcohol, paan, khat.
Persistent inflammation.

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3
Q

What is the main aetiological factors for cancer of the oropharynx ?

A

Local carcinogens - smoking, alcohol, paan, khat.
Persistent inflammation.
HPV.

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4
Q

What things would make you consider urgent suspicion of cancer referral ?

A

Head and neck lump persisting for >3 weeks.
Unexplained ulceration persisting for >3 weeks.
Unexplained red or mixed red and white patches persisting >3 weeks.
Persistent hoarseness lasting >3 weeks.
Persistent pain in throat or pain on swallowing lasting >3 weeks.

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5
Q

What are some common symptoms of oral cancer affecting bone ?

A

Trismus. Jaw fracture. Unexplained loosening of teeth. Acquired malocclusion.

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6
Q

What are some common symptoms of oropharyngeal cancer ?

A

Dysarthria. Unilateral earache. Pain on eating. Unexplained weight loss. Coughing blood.

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7
Q

What are some common symptoms of oral cancer affecting mucosa ?

A

Pain on eating. Submucosal mass lesion. Numbness of face. Verrucous lesion. Hemi-tongue atrophy/fasciculation. Nasal obstruction or blood stained rhinorrhoea.

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8
Q

In cancer staging and grading, what is Stage T cancer ?

A

Primary tumour.

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9
Q

In cancer staging and grading, what is Stage N cancer ?

A

Regional lymph nodes.

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10
Q

In cancer staging and grading, what is Stage M cancer ?

A

Distant metastasis.

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11
Q

What does cN0 mean ?

A

No lymph node involvement.

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12
Q

What levels of lymph nodes are most relevant to oral cancer and should be removed during primary resection in a cN0 patient ?

A

Level 1, 2, 3.
Will have microscopic metastases and should be removed in primary resection of the tumour.

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13
Q

Define sentinel nodes.

A

Those with direct lymphatic afferent from the primary tumour.

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14
Q

What is the toxicity of cancer treatment ?

A

Xerostomia.

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15
Q

What are late toxicity features of cancer treatment ?

A

ORN, fibrosis/vascular depletion, dysphagia, flexion deformity, trismus, hypothyroidism.

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16
Q

What is the consequences of radiation induced hypothyroidism ?

A

Root resorption. Poor periodontal health. Delayed wound healing.

17
Q

What % of patients develop radiation induced hypothyroidism after SCC treatment ?

A

22%