Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Endocrine > 2: Hyperprolactinaemia > Flashcards

2: Hyperprolactinaemia Flashcards

1
Q

Define hyperprolactinaemia

A

Prolactin concentration >390

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Define hyperprolactinaemia

A

Prolactin concentration >390

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the most common endocrine disorder of the pituitary gland

A

Hyperprolactinaemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the 3 mechanisms of hyperprolactinaemia

A

Prolactin-secreting tumour

Compression pituitary stalk (transmits dopamine from hypothalamus to pituitary gland)

Dopamine inhibition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are 3 physiological causes of high prolactin

A

Pregnancy
Breast Feeding
Stress

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the most common cause of high protection

A

Dopamine antagonists

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What group of medications cause hpyerprolactinaemia and why

A

Dopamine antagonists. As dopamine, released by the hypothalamus, inhibits prolactin release.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Name anti-dopaminergic medications

A

Metclopramide

Antipsychotics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What two tumours can cause hyperprolacintaemia

A

Prolactinoma

Craniopharyngioma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

In which gender are symptoms of high protecting usually first identified

A

Female - as symptoms are more obvious

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are symptoms of increase prolactin in females

A

Galactorrhoea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are symptoms of decrease FSH and LH in females

A
  • Amenorrhoea

- Infertility

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are symptoms of decreased testosterone in males

A
  • ED
  • Loss Libido
  • Gynaecomastia
  • Infertility
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are symptoms of decrease testosterone in females

A
  • Loss libido
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are symptoms of decrease oestrogen in females

A
  • Vaginal dryness

- Osteoporosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is first line investigation in suspected hyperprolactinaemia

A

Serum prolactin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What imaging is performed in hyperprolactinaemia

A

MRI Head

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What does management of prolactinoma depend on

A

microprolactinoma or macroprolactinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is a microprolactinoma

A

tumour less than 10mm on MRI

20
Q

What is first-line in microprolactinoma

A

Bromocriptine

21
Q

What is bromocriptine

A

Dopamine agonist

22
Q

What is a macroprolactinoma

A

tumour more than 10mm on MRI

23
Q

What is problem with macroprolactinoma

A

compress optic chiasm causing visual disturbance

24
Q

What is indicated in macroprolactinoma

A

trans sphenoidal surgical resection

25
Q

What is the most common endocrine disorder of the pituitary gland

A

Hyperprolactinaemia

26
Q

What are the 3 mechanisms of hyperprolactinaemia

A

Prolactin-secreting tumour

Compression pituitary stalk (transmits dopamine from hypothalamus to pituitary gland)

Dopamine inhibition

27
Q

What are 3 physiological causes of high prolactin

A

Pregnancy
Breast Feeding
Stress

28
Q

What is the most common cause of high protection

A

Dopamine antagonists

29
Q

What group of medications cause hpyerprolactinaemia and why

A

Dopamine antagonists. As dopamine, released by the hypothalamus, inhibits prolactin release.

30
Q

Name anti-dopaminergic medications

A

Metclopramide

Antipsychotics

31
Q

What two tumours can cause hyperprolacintaemia

A

Prolactinoma

Craniopharyngioma

32
Q

In which gender are symptoms of high protecting usually first identified

A

Female - as symptoms are more obvious

33
Q

What are symptoms of increase prolactin in females

A

Galactorrhoea

34
Q

What are symptoms of decrease FSH and LH in females

A
  • Amenorrhoea

- Infertility

35
Q

What are symptoms of decreased testosterone in males

A
  • ED
  • Loss Libido
  • Gynaecomastia
  • Infertility
36
Q

What are symptoms of decrease testosterone in females

A
  • Loss libido
37
Q

What are symptoms of decrease oestrogen in females

A
  • Vaginal dryness

- Osteoporosis

38
Q

What is first line investigation in suspected hyperprolactinaemia

A

Serum prolactin

39
Q

What imaging is performed in hyperprolactinaemia

A

MRI Head

40
Q

What does management of prolactinoma depend on

A

microprolactinoma or macroprolactinoma

41
Q

What is a microprolactinoma

A

tumour less than 10mm on MRI

42
Q

What is first-line in microprolactinoma

A

Bromocriptine

43
Q

What is bromocriptine

A

Dopamine agonist

44
Q

What is a macroprolactinoma

A

tumour more than 10mm on MRI

45
Q

What is problem with macroprolactinoma

A

compress optic chiasm causing visual disturbance

46
Q

What is indicated in macroprolactinoma

A

trans sphenoidal surgical resection

Endocrine (20 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions