2. human blood groups Flashcards
the production of antibodies against antigen A and B is by…
intestinal microorganisms whose cell wall antigens are the same as the antigens in the AB0 blood group
immunotolerance
the immune system tolerates its own RBC antigen shortly after birth
what are the antibodies type IgM?
antibodies against the A and B antigens and cannot go through the placenta
what can happen after an incompatible blood transfusion?
intravascular hemolysis- fever, shock, acute uremia or even death
what are the genes making the Rh antigens? (3)
C D and E.
if an individual’s genotype has at least one of the C D E antigens= positive Rh
what type of antigen is the anti-D
IgG type
what happens to an individual which is Rh negative if Rh
positive gets into his blood?
anti-D antigens (IgG type)
human blood group types is based on..
hemagglutination: hemagglutinins react with red blood cells that have antigens that the haemagglutinin recognizes. If a reaction takes place, visible clumps form and the surrounding serum becomes clear
what can happen if the blood type test takes place at a lower temp. than room temp.?
a non specific “cold agglutination” (even type 0 RBC agglutinate)