2 Flashcards

1
Q

Where is fatty acid broken down

A

Mitochondria

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2
Q

Degradation of fatty acid simple schematic

A

Oxidation then hydration then oxidation then cleavage

Synthesis opposite

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3
Q

Degradation of fatty acids

A

Oxidative process - B oxidation

  1. Oxidation - Introduced double bound using a dehydrogenase and FAD
  2. Double hydrated by a hydrotase introducing an OH
  3. Hydroxyl is oxidised to a ketone using a dehydrogenase and NAD+
  4. Fatty acid cleavage to give Acetyl CoA using a thiolase
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4
Q

Absorption synthesis and storage

A

.

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5
Q

What must fatty acids become before entering the mitochondria

A

must be activated through the formation of a thioester linkage to co-enzyme A

takes place in outer mitochondrial membrane

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6
Q

Ketone bodies

A

Are formed from acetyl CoA when fat breakdown predominates in liver

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