2/18/16 Wound healing

Question 1

effects of radiation on a wound

Answer 1

decrease vascularity, decreased oxygen tension, edema of collagen bundles and direct injury to fibroblasts, hyperkeratotic edges

Question 2

Incision strength percentages

Answer 2

1 week = 5%
2 weeks = 10%
3 weeks = 20%
4 weeks = 40%
6 weeks = 80%
12 week = 100%

Question 3

Treatment of Calcium IV infiltration

Answer 3

hyaluronidase

Question 4

Treatment of norepi/dopamine infiltration

Answer 4

phentolamine (alpha-blocker)

Question 5

treatment of vinca alkaloid extrav

Answer 5

topical heat

Question 6

Treatment of doxorubicin extrav

Answer 6

dexrazoxane, DMSO

Question 7

Types of rejection

Answer 7

Hyperacute = minutes
Acute = 0-3 months
chronic = years

Question 8

management of cutis aplasia

Answer 8

small defect - local wound care

large defect - skin graft, allograft, ADM, flap

Question 9

order of appearance of cells in a wound

Answer 9

appearance of cell types in an acute wound occurs in the following order:
platelets, neutrophils, macrophages, lymphocytes, and fibroblasts, during the inflammatory phase.

Question 10

phases of wound healing

Answer 10

inflammation, collagen synthesis, angiogenesis, epithelialization, and remodeling