1.9 enzyme inhibition Flashcards

1
Q

what are competitive inhibitors?

A

binds to & blocks the active site, slows rate of binding
- similar shape to substrate

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2
Q

how does substrate concentration affect the effectiveness of competitive inhibitors?

A

as substrate concentration increases, inhibitory effect decreases

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3
Q

what are non-competitive inhibitors?

A
  • binds to a different site on the enzyme which changes the shape of active site
  • makes the enzyme non-functional since substrate doesn’t bind
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4
Q

how does substrate concentration affect the effectiveness of non-competitive inhibitors?

A

no effect on inhibition level

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