17. Thorax II - Lungs Flashcards
What is the first stage of lung development?
The Glandular stage (weeks 5-17), Respiration is not possible, premature fetuses cannot live.
What is the second stage of lung development?
The Canalicular stage (weeks 13-25) Respiration is not possible, premature fetuses rarely survive.
What is the third stage of lung development?
The Termaninal sac stage (weeks 24-birth). Type I and II pneumocytes are present. Respiration is possible, premature fetuses born between weeks 25-28 can survive with intensive care.
What is the forth stage of lung development?
The Alveolar stage (Birth-8 years). Respiratory bronchioles, terminal sacs, alveolar ducts, and alveoli increase in number. Chest radiograph is more dense in children.
What is Respiratory distress syndrome?
Caused by surfactant insuficiency (composed of phosphatidylcholine [mainly dipalmitoyl lecithin] and proteins). This condition can be assiciated with premature infants, infants of diabetic mothers, and prolonged intrauterine asphyxia. Thyroxine and cortisol treatment increase the production of surfactant.
What is Hyaline membrane diasease?
Surfactant deficiency may lad to hyaline membrane disease whereby repeated gasping inhaltions damage the alveolar lining. Hyaline membrane disease si characterized histologically by collapsed alveoli (actelectasis) and eosinophilic (pink) fluid covering the alveoli.
What is difference between parietal pleura and visceral pleura?
Parietal pleura lines the inner surface of the thoracic cavity; visceral pleura follows the contours of the lung itself.
What can cause pulmonary hypoplasia?
It is when lung development is stunted. Can be caused by congenital diaphragmatic hernia (herniation fo abdominal contents into the thorax, which compresses the lung) or with bilateral renal agenesis (this causes oligohydramnios, which increases the pressure on the fetal thorax).
What is the pleural cavity?
It is the space between the parietal and visceral layers of the pleura. It is a sealed, blind space. The introduction of air into the pleural cavity may cause the lung to collapse (pneumothorax).
What makes the serous fluid found in the pleural cavity?
The mesothilia cells of the pleural membrane. It normally contains a small amount of fluid.
What are pleural reflections?
They are areas where the pleura change direction from one wall to the other.
What is the sternal line of reflection?
It is where the costal pleura is continuos with the mediastinal pleura behind the sternum (from costal cartilage 2-4). The pleural margin then passes inferiorly to the level of the sixth costal cartilage.
What is the costal line of reflection?
It is where the costal pleura becomes continuous with the diaphragmatic pleura from rib 8 in the midclavicular line, to rib 10 in the midaxillary line, and to rib 12 laterl to the vertebral column.
What are pleural recesses?
They are potential spaces not occupied by lung tissue except during deep inspiration.
Describe the costodiaphragmatic recess.
They are the spaces below the inferior borders of the lungs where costal and diaphragmatic pleura are in contact.