1.7: Microbiology Flashcards

1
Q

True or False:

Most sore throats are bacterial?

A

False

The majority (over 2/3rds) of sore throats are viral

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2
Q

What is the most common cause of bacterial throat infection?

A

Streptococcus Pygoenes (Group A Strep)

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3
Q

Treatment for Strep Throat?

A

Penicillin

Clarithromycin if allergic

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4
Q

Describe how strep pyogenes looks?

A

Gram Positive Cocci Chains

Beta Haemolysis on blood agar

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5
Q

Describe the acute complications of strep throat?

A

Quinsy - Peritonsilar Abscess (needs drained)

Sinusitis/Otitis Media

Scarlet Fever

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6
Q

Describe some later complications of strep throat?

A

Rheumatic Fever - fever, arthritis, endocarditis

Glomerulonephritis

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7
Q

What does this photo show?

A

Peritonsillar Abscess

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8
Q

Describe Diptheria?

A

Severe sore throat

Grey membrane across the pharynx

Produces a toxin which is cardiotoxic and neurotoxic

Can lead to respiratory arresst

Uncommon in UK due to vaccination

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9
Q

What condition does this show?

A

Diptheria (Classic Bulls Neck appearance)

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10
Q

Describe Candida?

A

Oral thrush

Presents as white patches on red, raw mucous membranes in the throat and mouth

Treatment with Nyastin suspension orally

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11
Q

Describe Acute Otitis Media?

A

Infection/inflammation of the middle ear by extension of infection up the eustachian tube

Seen in children and babies

Presents with ear ache

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12
Q

What are the most common causative organisms of middle ear infections?

Diagnosis?

A

Usually viral with bacterial secondary infection

  • Haemophilus Infuenza
  • Streptococcus pneumoniae
  • Streptococcus pyogenes

Swab of pus if eardrum perforates, it not then no swab

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13
Q

Treatment of middle ear infections?

A

80% resolve in 4 days without antibiotics

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14
Q

Describe acute sinusitis?

A

Infection in the frontal or maxillary sinuses

Often seen in patients with upper respiratory viral infections

Usually self limiting

However, severe pain/tenderness and purulent discharge suggests secondary bacterial infection which needs Penicillin

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15
Q

Describe Otitis externa?

Causes?

A

This is inflammation of the outer ear canal

Often called swimmers ear

Causes red, itchy, painful, swollen ear with some possible discharge and hearing loss

Bacteria; Staph aureus, proteus

Fungal: Aspergillus, candida

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16
Q

What does this photo show?

A

Fungal Otitis Externa

17
Q

What does this photo show?

A

Otitis Externa (Bacterial)

18
Q

How do you treat otitis externa?

A
  • Washout ear

Acetic Acid 2% for bacterial

Clotrimazole (Canesten) for fungal

Topical gentamycin for pseudomonas

19
Q

Describe infectious mononucleosis?

A

Mono/Glandular Fever

Disease of young adults causing fever, enlarged lymph nodes, sore throat, malaise, lethargy

CLASSIC TRIAD: FEVER, PHARYNGITIS, LYMPHAEDNOPATHY

20
Q

What causes infectious mononucleosis?

Treatment?

A

EBV (Ebstein Barr Virus)

Bed rest, paracetamol, fluids

Avoid contact sports

21
Q

What causes oral ulcers?

A

HSV1 (Herpes Simplex 1)

22
Q

Describe primary gingivostomatitis?

A

HSV1 infection

Causes oral ulcers, systemic upset

Seen in pre-school children

May take up 3 months to recover

Aciclovir can be used

23
Q

How do you confirm HSV?

A

PCR from swab

24
Q

What does this show?

Symptoms?

A

Herpes Simplex Encephalitis

Fever, personality changes

25
Q

Describe Herpangina?

  • Cause?
  • Who?
  • Diagnosis?
A

Causes vesicles and ulcers on the soft palate

Caused by coxsackie virus, not HSV

Seen in pre school children

Diagnosis using PCR

26
Q

What does this photo show?

A

Herpangina

27
Q

Describe hand foot and mouth disease?

A

Also caused by Coxsackie virus

Causes fever, malaise, loss of appetite, skin rash and herpangina

Seen in children < 5

Family outbreaks common

28
Q

Describe Apthous ulcers?

A

Recurrent mouth ulcers

Round or oval

Have inflammatory halos

Confined to mouth, no systemic disease

29
Q

Describe Chancre?

A

Painless ulcers

Can be oral or genital

Primary sphylliss

If untreated can progress to secondary