1.7 Lymphoproliferative and Myeloproliferative Disorders Flashcards
Repeated phlebotomy in patients with PV may lead to the development of:
A. Folic acid deficiency
B. Sideroblastic anemia
C. IDA
D. Hemolytic anemia
In ET, the PLTs are:
A. Increased in number and functionally abnormal
B. Normal in number and functionally abnormal
C. Decreased in number and functional
D. Decreased in number and functionally abnormal
Which of the following cells in considered pathognomonic for Hodgkin disease?
A. Niemann-Pick cells
B. Reactive lymphocytes
C. Flame cells
D. Reed-Sternberg (RS) cells
In myelofibrosis, the characteristic abnormal RBC morphology is that of:
A. Target cells
B. Schistocytes
C. Teardrop-shaped cells
D. Ovalocytes
PV is characterized by:
A. Increased plasma volume
B. Pancytopenia
C. Decreased O2 saturation
D. Absolute increase in total RBC mass
Features of secondary polycythemia include all of the following except:
A. Splenomegaly
B. Decreased O2 saturation
C. Increased RBC mass
D. Increased erythropoietin
Erythrocytosis in relative polycythemia occurs because of:
A. Decreased arterial O2 saturation
B. Decreased plasma volume of circulating blood
C. Increased erythropoietin levels
D. Increased erythropoiesis in bone marrow
In PV, what is characteristically seen in peripheral blood?
A. Panmyelosis
B. Pancytosis
C. Pancytopenia
D. Panhyperplasia
Leukocyte alkaline phosphatase (LAP) staining performing on a patient gives the following results:
10(0)
48(1+)
38(2+)
3(3+)
1(4+)
Calculate the LAP score
A. 100
B. 117
C. 137
D. 252
CML is distinguished from leukemoid reaction by which of the following?
A. CML: low LAP; leukemoid; high LAP
B. CML: high LAP; leukemoid: low LAP
C. CML: high WBC; leukemoid: normal WBC
D. CML: high WBC; leukemoid: higher WBC
Which of the following occurs in idiopathic myelofibrosis (IMF)?
A. Myeloid meta plasma
B. Leukoerythroblastosis
C. Fibrosis of bone marrow
D. All of these options
