[16.5] control of blood water potential - structure of nephron Flashcards

1
Q

what is osmoregulation?

A

the homeostatic control of the water potential of the blood

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2
Q

what does blood plasma contain? (6)

A
  • water
  • urea
  • glucose
  • ions (Na, Cl etc.)
  • plasma proteins
  • amino acids
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3
Q

where does urea come from?

A
  • nitrogenous waste
  • we can’t store excess AA in the basic structure form
  • you can use one AA to make another by changing the R groups
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4
Q

how does deamination occur?

A
  1. remove the R group
  2. slice NH₃ / COOH
  3. COOH can be used as a respiratory substrate
  4. ammonia (NH₃) is the main toxic waste product
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5
Q

what is NH₃ converted into?

A
  • NH₃ is too toxic
  • converted into urea
  • urea is not toxic enough that it can go through liver to kidneys etc.
  • ammonia + carbon dioxide -> urea
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6
Q

what are the different components of the kidney? (7)

A
  • fibrous capsule
  • cortex
  • medulla
  • renal pelvis
  • ureter
  • renal artery
  • renal vein
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7
Q

what is the fibrous capsule?

A

outer membrane that protects the kidney

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8
Q

what is the cortex?

A
  • lighter coloured outer region
  • made up of renal (bowman’s) capsules, convoluted tubules and blood vessels
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9
Q

what is the medulla?

A
  • darker coloured inner region
  • made up of loops of henle, collecting ducts and blood vessels
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10
Q

what is the renal pelvis?

A

funnel-shaped cavity that collects urine into the ureter

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11
Q

what is the ureter?

A

tube that carries urine to the bladder

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12
Q

what does the renal artery do?

A

supplies oxygenated blood to kidney from the heart via the aorta

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13
Q

what does the renal vein do?

A
  • removes blood from kidney
  • returns deoxygenated blood to the heart via the vena cava
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14
Q

how do renal arteries and veins differ?

A

different compositions ie. concentrations of substances in the blood plasma

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15
Q

what is a nephron?

A

functional unit of the kidney

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16
Q

what are the different components of a nephron? (5)

A
  • renal (bowman’s) capsule
  • proximal convoluted tubule (PCT)
  • loop of henle
  • distal convoluted tubule
  • collecting duct
17
Q

what are podocytes?

A

specialised cells making up the inner layer of bowman’s capsule

18
Q

describe the proximal convoluted tubule

A
  • series of loops surrounded by blood capillaries
  • walls made of epithelial cells which have microvilli
19
Q

describe the loop of henle

A
  • loop that extends from the cortex into the medulla of the kidney and back again
  • has descending limb and ascending limb
  • surrounded by blood capillaries
20
Q

describe the distal convoluted tubule

A
  • series of loops surrounded by blood capillaries
  • surrounded by fewer capillaries than PCT
  • walls are made of epithelial cells
21
Q

describe the collecting duct

A
  • where many DCTs from many nephrons empty
  • lined by epithelian cells
  • becomes increasingly wide as it empties into the pelvis of the kidney
22
Q

what are the blood vessels associated with each nephron? (4)

A
  • afferent arteriole
  • glomerulus
  • efferent arteriole
  • blood capillaries
23
Q

describe the afferent arteriole

A
  • arises from renal artery
  • supplies nephron with blood
  • afferent arteriole enters bowman’s capsule where it forms the glomerulus
24
Q

describe the glomerulus

A
  • mass of blood capillaries in bowman’s capsule
  • where fluid is forced out of the blood
  • glomerular capillaries recombine to form the efferent arteriole
25
describe the efferent arteriole
- leaves renal capsule - smaller diameter than afferent arteriole, causing an increase in blood pressure in the glomerulus - carries blood away from bowmna's capsule - later branches to form the blood capillaries
26
describe the blood capillaries in the nephron
- concentrated network surrounds the PCT, LoH and DCT - reabsorb mineral salts, glucose and water - merge together into venules, which merge to form the renal vein