[16.4] diabetes and its control Flashcards
what is diabetes?
a metabolic disorder caused by an inability to control blood glucose concentration due to a lack of insulin or a loss of responsiveness to insulin
what are the 2 types of diabetes?
- type 1 (insulin dependent)
- type 2 (insulin independent)
what causes type 1 diabetes?
autoimmune condition whereby the immune system destroys β cells of islets of langerhans preventing the production of insulin
what causes type 2 diabetes?
- glycoprotein receptors on cells lose their responsiveness to insulin
- inadequate supply of insulin from the pancreas
describe the differences between the 2 types of diabetes (3)
- 1 normally begins in childhood, 2 usually develops 40+
- 1 develops quickly (usually over a few weeks), 2 develops slowly
- 1’s signs and symptoms are normally obvious, 2 has less severe symptoms which may go unnoticed
what are the signs and symptoms of diabetes?
- high blood glucose concentration
- presence of glucose in urine
- need to urinate excessively
- genital itching
- regular episodes of thrush
- weight loss
- blurred vision
- tiredness
- increased thirst and hunger
why is tiredness / weight loss a sign of diabetes?
- decreased respiration rate
- glucose remains in cells so cellular respiration drops
- other stores are used up
why is thirst / need to urinate excessively a sign of diabetes?
- glucose dissolved in blood plasma makes the water potential more negative
- water moves from body’s cells and tissues into the bloodstream via osmosis
- excess is drained into urine production
- more water is lost so more is needed to replace it
how is type 1 diabetes treated?
- injections of insulin 2-4 times a day matched precisely o a person’s glucose intake
- blood glucose level can be monitored with biosensors
- pancreas transplant is an option
- managing carbohydrate intake and exercise
how is type 2 diabetes treated?
- regulating intake of carbohydrate matched to amount of exercise taken
- drugs which slow down rate at which body absorbs glucose from intestine