[16] Other Gastric Neoplasms Flashcards
Give 5 benign neoplasms of the stomach
Benign polyps Leiomyoma Lipomas Haemangiomas Schwannomas
Give 3 malignant gastric neoplasms
Lymphoma
Carcinoid
GIST
What is the most common mesenchymal tumour of the GIT?
Gastrointestinal stromal tumour
What % of gastrointestinal stromal tumours occur in the stomach?
> 50%
When do gastrointestinal stromal tumours occur?
About 60 years
What genetic condition has an increased incidence of gastrointestinal stromal tumours?
Neurofibromatosis type 1
Where do gastrointestinal stromal tumours arise from?
Intestinal cells of Cajal
Where are the intestinal cells of Cajal located?
In the muscularis propria
What is the function of the intestinal cells of Cajal?
Pacemaker cells
What is found on OGD in gastrointestinal stromal tumours?
Well-demarcated spherical mass with central punctum
What causes the presentation of gastrointestinal stromal tumours?
Mass effects
Ulceration
What symptoms are caused by mass effects in gastrointestinal tumours?
Abdominal pain
Obstruction
What symptoms are caused by ulceration in gastrointestinal stromal tumours?
Bleeding
What are the poor prognostic factors in gastrointestinal stromal tumours?
Large size
Extra-gastric location
Increased mitotic index
What is involved in the medical management of gastrointestinal stromal tumours?
Imatinib