16. CP Gas Transport Flashcards
What is the solubility of O2 in plasma?
0.3 ml O2 / dl blood / 100 mmHg
What is the average O2 content of arterial blood?
What is the oxygen content of blood at 100& saturation?
Average = 20 mlO2 / dl blood (200ml O2 / L)
At 100% = 20.1 mlO2 / dl blood
What results in a right shift (lower affinity) of oxygen binding?
High CO2
High Temperature
2,3 BPG
(Eg. Being in the tissues)
What is the O2 saturation in venous blood?
What is the O2 content in venous blood?
Saturation in venous blood = 75%
O2 content in venous blood = 15.2 ml O2
What is the arterial - venous O2 difference?
Include definition and value.
Definition: The difference between the content of O2 in the arterial blood vs venous blood. (How much O2 was used.)
Value: 4.6 mlO2 / dl blood difference
What is the CO2 production vs O2 consumption for:
Carbohydrates
Fatty Acids
Carbohydrates 1/1
Fatty Acids: 7 CO2 : 10 O2
What is the average CO2 produced / O2 consumed for all fuels combined? (Experimental average)
8 CO2 : 10 O2
(.8)
What is the equation for respiratory quotient (RQ)?
CO2 produced / O2 consumed
What three forms can CO2 take when transported in the blood?
Dissolved
Carbamino compounds (bound to amines)
As bicarbonate
What is the solubility of CO2 in blood plasma?
6ml CO2 / dl blood / 100 mmHg
(20x higher than O2)
What is the CO2 content in blood?
2.7 ml CO2 / dl
What is the Haldane Shift?
The phenominon by which O2 changes the conformation of Hb to reduce the affinity of Hb for CO2
How much CO2 is carried as cabamindo compounds?
3ml CO2 / dl of blood