16. Common medications Flashcards
Name indications/comments of drug: betamethasone valerate (Celestone®)
Enhancement of fetal pulmonary maturity for preterm labour
Describe dosing schedule: betamethasone valerate (Celestone®)
12 mg IM q24h x 2 doses
Name indications/comments of drug: carboprost (Hemabate®)
Treatment of uterine atony
Describe dosing schedule: carboprost (Hemabate®)
- 0.25 mg IM/IMM q15min
- Max 2 mg
Name indications/comments of drug: cefazolin
Group B Streptococcus prophylaxis (penicillin allergic and not at risk for anaphylaxis)
Describe dosing schedule: cefazolin
2 g IV then 1 g q8h
Name indications/comments of drug: clindamycin
Used in endometritis
Describe dosing schedule: clindamycin
900 mg IV q8h
Name indications/comments of drug: dinoprostone (Cervidil®: PGE2 impregnated thread)
- Induction of labour
- Advantage: can remove if uterine hyperstimulation
Describe dosing schedule: dinoprostone (Cervidil®: PGE2 impregnated thread)
- 10 mg PV (remove after 12 h)
- Max 3 doses
Name indications/comments of drug: doxylamine succinate (Diclectin®)
- Each tablet contains 10 mg doxylamine succinate with vitamin B6
- Used first-line for N/V in pregnancy, including hyperemesis gravidarum
Describe dosing schedule: doxylamine succinate (Diclectin®)
- 2 tabs qhs + 1 tab qam + 1 tab qpm
- Max 8 tabs/d
Name indications/comments of drug: erythromycin
GBS prophylaxis (penicillin allergic and at risk for anaphylaxis)
Describe dosing schedule: erythromycin
500 mg IV q6h
Name indications/comments of drug: folic acid
Prevention of open neural tube defect ONTD
Describe dosing schedule: folic acid
0.4-1 mg PO OD x 1-3 mo preconception and T1 5 mg PO OD with past Hx of NTD/risks for NTD
Name indications/comments of drug: methotrexate
For ectopic pregnancy or medical abortion
Describe dosing schedule: methotrexate
50 mg/mL IM or 50 mg PO x 1 dose
Name indications/comments of drug: methylergonavine maleate (Ergotamine®)
Treatment of uterine atony
Describe dosing schedule: methylergonavine maleate (Ergotamine®)
- 0.25 mg IM/IMM q15min up to 1.25 mg
- or IV bolus 0.125 mg
Name indications/comments of drug: misoprostol (Cytotec®)
- For treatment of postpartum hemorrhage PPH
- For medical abortion/retained products of conception
Describe dosing schedule: misoprostol (Cytotec®)
- 600-1000 µg PR x 1 dose
- 400 µg PO/SL x 1 dose
- or 800 µg PV x 1 dose 3-7 d after methotrexate
Name indications/comments of drug: oxytocin (Pitocin®)
- Augmentation of labour (also induction of labour)
- Prevention of uterine atony
- Treatment of uterine atony
Describe dosing schedule: oxytocin (Pitocin®)
- 0.5-2.0 mU/min IV or 10 U/L NS increase by 1-2 mU/min q20-60min
- Max 36-48 mU/min
- 10 IU IM at delivery of anterior shoulder and of placenta 20 IU/L NS or RL IV continuous infusion
Name indications/comments of drug: Penicillin G
GBS prophylaxis
Describe dosing schedule: Penicillin G
5 million IU IV, then 2.5 million IU IV q4h until delivery
Describe dosing schedule: PGE2 gel (Prostin® gel)
Induction of labour
Describe dosing schedule: PGE2 gel (Prostin® gel)
- 0.5 mg PV q6-12h
- max 3 doses
Name indications/comments of drug: Rh IgG (Rhogam®)
- Given to Rh-negative women
- Routinely at 28 wk GA
- Within 72 h of birth of Rh+ fetus
- Positive Kleihauer-Betke test
- With any invasive procedure in pregnancy
- Ectopic pregnancy
- Antepartum hemorrhage
- Miscarriage or therapeutic abortion (dose: 50 µg IM only)
Describe dosing schedule: Rh IgG (Rhogam®)
300 µg IM x 1 dose
