11. Induction of Labour Flashcards
Define: Induction of labour (1)
artificial initiation of labour in a pregnant woman prior to spontaneous initiation to deliver the fetus and placenta
Name Prerequisites for Labour Induction (3)
- capability for C/S if necessary
- maternal: inducible/ripe cervix: short, thin, soft, anterior cervix with open os
- fetal:
- normal fetal heart tracing
- cephalic presentation
- adequate fetal monitoring available
If cervix is not ripe for induction of labour, what to do? (4)
- prostaglandin vaginal insert (Cervidil®)
- prostaglandin gel (Prepidil®)
- misoprostol (Cytotec®)
- Foley catheter
Induction is indicated when? (1)
when the risk of continuing pregnancy exceeds the risks associated with induced labour and delivery
Likelihood of success of induction of labour determined by what? (3)
Bishop score
- cervix considered unfavourable if <6
- cervix favourable if ≥6
- score of 9-13 associated with high likelihood of vaginal delivery
Name cervical characteristics in Bishop score (5)
- Position
- Consistency
- Effacement (%)
- Dilatation (cm)
- Station of Fetal Head
Describe Bishop Score 0
- Position
- Consistency
- Effacement (%)
- Dilatation (cm)
- Station of Fetal Head
- Position: Posterior
- Consistency: Firm
- Effacement (%): 0-30
- Dilatation (cm): 0
- Station of Fetal Head: -3
Describe Bishop Score 1
- Position
- Consistency
- Effacement (%)
- Dilatation (cm)
- Station of Fetal Head
- Position: Mid
- Consistency: Medium
- Effacement (%): 40-50
- Dilatation (cm): 1-2
- Station of Fetal Head: -2
Describe Bishop Score 2
- Position
- Consistency
- Effacement (%)
- Dilatation (cm)
- Station of Fetal Head
- Position: Anterior
- Consistency: Soft
- Effacement (%): 60-70
- Dilatation (cm): 3-4
- Station of Fetal Head: -1,0
Describe Bishop Score 3
- Position
- Consistency
- Effacement (%)
- Dilatation (cm)
- Station of Fetal Head
- Position: -
- Consistency: -
- Effacement (%): _>_80
- Dilatation (cm): _>_5
- Station of Fetal Head: +1, +2, +3
Differentiate: Induction vs. Augmentation (2)
- Induction is the artificial initiation of labour
- Augmentation promotes contractions when spontaneous contractions are inadequate
Name indications of induction (4)
- post-dates pregnancy (generally >41 wk) = most common reason for induction
- maternal factors
- maternal-fetal factors
- fetal factors
Name MATERNAL indications of induction (5)
- DM = second most common reason for induction
- gestational HTN ≥37 wk
- preeclampsia
- other maternal medical problems, e.g. renal or lung disease, chronic hypertension, and cholestasis
- maternal age over 40
Name MATERNAL-FETAL indications of induction (3)
- isoimmunization
- preterm premature rupture of membranes PROM
- chorioamnionitis
Name FETAL indications of induction (3)
- suspected fetal jeopardy as evidenced by biochemical or biophysical indications
- macrosomia, fetal demise, intrauterine growth restriction IUGR, oligo/polyhydramnios, anomalies requiring surgical intervention, and twins
- previous stillbirth or low pregnancy-associated plasma protein A (PAPP-A)
Name risks of induction (4)
- failure to achieve labour and/or vaginal birth
- uterine hyperstimulation with fetal compromise or uterine rupture
- maternal side effects to medications
- uterine atony and postpartum hemorrhage (PPH)
Name maternal contraindications (5)
- prior classical or inverted T-incision C/S or uterine surgery (e.g. myomectomy)
- unstable maternal condition
- active maternal genital herpes
- invasive cervical carcinoma
- pelvic structure deformities
Name maternal-fetal contraindications (2)
- placenta previa or vasa previa
- cord presentation
Name fetal contraindications (3)
- fetal distress
- malpresentation/abnormallie
- preterm fetus without lung maturity
Consider the Following Before Induction… (8)
- Indication for induction
- Contraindications
- GA
- Cervical favourability
- Fetal presentation
- Potential for CPD
- Fetal well-being/FHR
- Membrane status
Describe: Cervical ripening (2)
- use of medications or other means to soften, efface, and dilate the cervix; increases likelihood of successful induction
- ripening of an unfavourable cervix (Bishop score <6) is warranted prior to induction of labour
Name methods of cervical ripening (4)
-
intravaginal prostaglandin PGE2 gel (Prostin® gel): long and closed cervix
- recommended dosing interval of prostaglandin gel is every 6-12 h up to 3 doses
-
intravaginal PGE2 (Cervidil®): long and closed cervix, may use if rupture of membranes ROM
- continuous release, can be removed if needed
- controlled release PGE2
- intracervical PGE2 (Prepidil®)
-
intravaginal PGE1 misoprostol (Cytotec®): long and closed cervix
- inexpensive, stored at room temperature
- more effective than PGE2 for achieving vaginal delivery and less epidural use
- Foley catheter placement to mechanically dilate the cervix
Name theoretical advantages of Intravaginal PGE2 Cervidil® (4)
- Slow, continuous release
- Only one dose required
- Ability to use oxytocin 30 min after removal vs. 6 hours for gel
- Ability to remove insert if required (i.e. excessive uterine activity)
Describe: Amniotomy (3)
- artificial ROM (amniotomy) to stimulate prostaglandin synthesis and secretion; may try this as initial measure if cervix is open and soft, the membranes can be felt, and if the head is present at the cervix
- few studies address the value of amniotomy alone for induction of labour
- amniotomy plus intravenous oxytocin: more women delivered vaginally at 24 h than amniotomy alone (relative risk = 0.03) and had fewer instrumental vaginal deliveries (relative risk = 5.5)
Describe oxytocin for induction of labor (5)
- oxytocin (Pitocin®): 10 U in 1L NS, run at 0.5-2 mU/min IV increasing by 1-2 mU/min q20-60min
- reduces rate of unsuccessful vaginal deliveries within 24 h when used alone (8.3% vs. 54%, RR 0.16)
- ideal dosing regimen of oxytocin is not known
- current recommendations: use the minimum dose to achieve active labour and increase q30min as needed
- reassessment should occur once a dose of 20 mU/min is reached
Name potential complications of oxytocin in induction of labor
- hyperstimulation/tetanic contraction (may cause fetal distress or uterine rupture)
- uterine muscle fatigue, uterine atony (may result in postpartum hemorrhage PPH)
- vasopressin-like action causing anti-diuresis