1.5.2: DNA Replication Flashcards
1
Q
Describe semi-conservative DNA replication
A
1) DNA helicase breaks hydrogen bonds between complementary base pairs between strands, unwinding the double helix.
2) Each separated strand acts as a template
3) Free DNA nucleotides are attracted to exposed complementary bases on template strands. Adenine to thymine and guanine cytosine.
4) DNA polymerase joins adjacent nucleotides through a condensation reaction forming phosphodiester bonds
5) Each DNA molecule has one original strand and a newly synthesised strand
2
Q
Who discovered the structure of DNA?
A
Watson and Crick
3
Q
Who proved DNA replicated semi conservatively?
A
Meselson and Stahl
