1.5 : The Origin of Cells Flashcards

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1
Q

what is spontaneous generation?

A

the belief that cells could rise spontaneously.

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2
Q

what is evolution?

A

the processes that have transformed life on earth from its earliest beginnings to the diversity of forms we know about today, of all living and extinct organisms.

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3
Q

what did Pasteur’s investigation disprove & how? & example?

A

Disproved spontaneous generation, by proving that there are spores of microorganisms in the air –> & when these reach favourable conditions, they germinate –> giving rise to large populations of microorganisms by cell division.
–> when nutrient liquids become cloudy –> nutrient solids grow visible colonies and moulds = a result of cell division of pre-existing cells.

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4
Q

what are the required steps that are required for the formation of living cells from non-living materials?

A
  • synthesis of simple organic molecules (amino acids, sugars)
  • assembly of these molecules into polymers (amino acids to proteins, etc)
  • development of self-replicating molecules (nucleic acids = nucleotides)
  • retention of these molecules within membranous sacs= internal chemistry developed (different from surrounding environment)
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5
Q

what are the main elements that make up living things?

A

carbon, hydrogen, oxygen (some nitrogen, phosphorous, sulphur & additional elements)

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6
Q

how did S.L. Miller & H.C. Urey investigate how simple organic molecules may have arisen from ingredients present on earth before life? what does this confirm?

A
  • by using a reaction vessel in which particular environmental conditions could be replicated –> used electromagnetic energy to generate strong electric sparks (simulating lightning) –> passed through mixtures of different gases (methane, ammonia, water vapour, etc) for a period of time –> all gases were cooled down as the spark went around –> amino acids (component of cell proteins) was formed & other compounds (nucleic bases, simple polymers)
  • confirmed that organic molecules can be synthesised outside of cells, in the absence of oxygen.
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7
Q

in the assembly of polymers of living things, what type of reaction occurs?

A

condensation reaction = anabolic –> building up of things = endergonic reaction - requires energy.

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8
Q

as no enzymes were present before, what type of environment was necessary?

A

need an environment with high heat and pressure.
–> allowing molecules to move around & vibrate a lot –> increased chance of collisions between molecules (due to absence of enzymes).

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9
Q

what is the advantage of sugars being present near volcanoes or lava flow?

A
  • a lot of sulphur, phosphorous, etc gases are present in these environments –> elements necessary for the build up of living things.
  • has ideal environment –> volcano = gas enclosed in rock –> temperature will rise, leading to an increase in pressure.
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10
Q

what does the evolution of life from a mixture of polymers and their monomers require?

A
  • a self-replication system

- the ability to catalyse chemical change.

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11
Q

what functioned as an enzyme and DNA before life, when these weren’t present?

A

RNA –> can function as an enzyme –> assume that RNA combined roles of ‘information molecules’ and ‘enzymes’ in the evolution of life.
–> short RNA molecules would’ve functioned as replication system & enzymes (catalyst) = but the catalytic activity of RNA is lower.

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12
Q

how are microspheres formed?

A

when more & more lipids are present (hydrophobic) –> bilayers are formed –> when there is a gap present somewhere in the lipid bilayer –> prebiotic soup enters
–> forms membrane systems with distinctive internal chemistry (different from external) –> microsphere formed. (not yet a cell)

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13
Q

what needs to generate for a microsphere to become a prokaryote?

A
  • enzymes generation of a circular chromosome that is a helical sequence of nucleotides (RNA or DNA)
  • generation of cell wall (some prokaryotes)
  • generation of enzymes (RNA doesn’t conduct this function anymore due to evolution)
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14
Q

what benefit did microspheres with proteins that developed enzymes have in the past?

A

they thrived better in the past –> had faster catalytic activity.

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15
Q

what occurs when prokaryotes form into eukaryotes & how do these form? (the endosymbiotic theory)

A

(nucleus, nuclear membrane, organelles needed)

  • formation of nucleus : chromosomes gathered in a sac of infolded plasma membrane until a nuclear membrane is formed.
  • organelles formed : may have ingested (and not digested) other prokaryotes with food –> these may have survived inside the host cell after being engulfed –> may have happened with mitochondria & chloroplast (seem to have their own DNA).
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16
Q

how do prokaryotes differ from microspheres?

A

have a circular chromosome attached to plasma membrane & cell wall of complex chemistry –> secreted outside membrane barrier.

17
Q

what is the evidence of the endosymbiotic theory?

A
  • chloroplasts & mitochondria contain circular DNA, like that of prokaryotes
  • prokaryotes are known to inhabit (live in) some eukaryotic cells.
  • chloroplast & mitochondria reproduce by binary fission, like prokaryotes (may have been engulfed & not digested in host cell = eukaryote)
  • chloroplast & mitochondria transcribe mRNA from their DNA & synthesise specific proteins in their ribosomes, as prokaryotes do.
  • chloroplasts and mitochondria contain ribosomes of the same size as those in prokaryotes.
18
Q

possible locations where conditions would have allowed for the synthesis of organic compounds?

A
  • Hydrothermal vents: Regions of the ocean floor where superheated water is released from the Earth’s crust.
  • Volcanoes: Intensive volcanic activity could provide sufficient thermal activity.
  • Extraterrestrial locations: Other planets (e.g. Mars) may have appropriate conditions.
19
Q

Outline two properties of RNA that would have allowed it to play a role in the origin of life.

A
  1. RNA can self-replicate
    - RNA is able to store information in a sequence of four nucleotides (similar to DNA).
    - Short sequences of RNA have been able to duplicate other molecules of RNA accurately.
  2. RNA can act as a catalyst
    - Modern cells use RNA catalysts (called ribozymes) to remove introns from mRNA and help synthesise new RNA molecules.
    - In ribosomes, rRNA is found in the catalytic site and plays a role in peptide bond formation
20
Q

Outline the contribution of prokaryotes to the creation of an oxygen-rich atmosphere, and what did this lead to?

A

-a form of chlorophyll evolved in prokaryotes (forming cyanobacteria) –> allowed for photosynthesis to occur, creating oxygen gas as a by-product of the photolysis (separation of molecules using light) of water.

lead to :

  • The breakdown of chemicals in the atmosphere and oceans = produced oxidised compounds (e.g. CO2)
  • The evolution of organisms capable of breaking down oxygen-rich oxidising agents
  • The formation of an ozone layer = restricted UV radiation = allowed for growth of a wider range of life forms.