15. Pregnancy and hematologic disorders

Question 1

The greatest risk of venous thromboembolism (VTE) is during?

Answer 1

during the first few weeks postpartum, especially following cesarean delivery.
Pregnancy represents a hypercoagulable state with up to 5-fold increased risk of deep vein thrombosis (DVT) and pulmonary embolism (PE).

Question 2

what anticoagulation shouldn’t be used in pregnancy?

Answer 2

warfarin and NOAC

Question 3

Diagnosis of DVT is confirmed with?

Answer 3

US or MRI
D-dimer test shouldn’t be used

Question 4

when should DVT be suspected?

Answer 4

in a patient with > 2 cm difference in calf circumference, history of immobility, history of hypercoagulability.

Question 5

Treatment for DVT in pregnancy

Answer 5

IV unfractionated heparin or LMWH (enoxaparin) for 5-7 days, followed by IM LMWH for the rest of the pregnancy and 6 weeks postpartum