1.5 Flashcards

1
Q

Which of the following is an unusual complication that may occur in infectious mononucleosis?

A. Splenic infarctions
B. Dactylitis
C. Hemolytic anemia
D. Giant platelets

A

C. Hemolytic anemia

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2
Q

In a patient with human immunodeficiency virus (HIV) infection, one should expect to see:

A. Shift to the left in WBCs
B. Target cells
C. Reactive lymphocytes
D. Pelgeroid cells

A

C. Reactive lymphocytes

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3
Q

Which inclusions may be seen in leukocytes?

A. Döhle bodies
B. Basophilic stippling
C. Malarial parasites
D. Howell-Jolly bodies

A

A. Döhle bodies

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4
Q

Which of the following is contained in the primary granules of the neutrophil?

A. Lactoferrin
B. Myeloperoxidase
C. Histamine
D. Alkaline phosphatase

A

B. Myeloperoxidase

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5
Q

What is the typical range of relative lymphocyte percentage in the peripheral blood smear of a 1-year-old child?

A. 1%-6%
B. 27%-33%
C. 35%-58%
D. 50%-70%

A

D. 50%-70%

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6
Q

Qualitative and quantitative neutrophil changes noted in response to infection include all of the following except:

A. Neutrophilia
B. Pelgeroid hyposegmentation
C. Toxic granulation
D. Vacuolization

A

B. Pelgeroid hyposegmentation

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7
Q

Neutropenia is present in patients with which absolute neutrophil counts?

A. <1.5 × 109/L
B. <5.0 × 109/L
C. <10.0 × 109/L
D. <15.0 × 109/L

A

A. <1.5 × 109/L

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8
Q

The morphological characteristic(s) associated with the Chédiak-Higashi syndrome is (are):

A. Pale blue cytoplasmic inclusions
B. Giant lysosomal granules
C. Small, dark-staining granules and condensed
nuclei
D. Nuclear hyposegmentation

A

B. Giant lysosomal granules

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9
Q

The familial condition of Pelger-Huët anomaly is important to recognize because this disorder must be differentiated from:

A. Infectious mononucleosis
B. May-Hegglin anomaly
C. A shift-to-the-left increase in immature granulocytes
D. G6PD deficiency

A

C. A shift-to-the-left increase in immature granulocytes

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10
Q

SITUATION: A differential shows reactive lymphocytes, and the physician suspects a viral infection is the cause. What is the expected laboratory finding in a patient with a cytomegalovirus (CMV) infection?

A. Heterophile antibody: positive
B. Epstein-Barr virus (EBV)-immunoglobulin (IgM): positive
C. Direct antiglobulin test (DAT): positive
D. CMV-IgM: positive

A

D. CMV-IgM: positive

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11
Q

Neutrophil phagocytosis and particle ingestion are associated with an increase in oxygen utilization called respiratory burst. What are the two most important products of this biochemical reaction?

A. Hydrogen peroxide and superoxide anion
B. Lactoferrin and NADPH oxidase
C. Cytochrome b and collagenase
D. Alkaline phosphatase and ascorbic acid

A

A. Hydrogen peroxide and superoxide anion

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12
Q

Which of the morphological findings are characteristic of reactive lymphocytes?

A. High nuclear:cytoplasmic ratio
B. Prominent nucleoli
C. Basophilic cytoplasm
D. All of these options

A

D. All of these options

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