1.5

Question 1

Define Drug

Answer 1

Chemical agent that has a biological effect

Question 2

Curative vs. Palliative

Answer 2

Curative - cures a disease (drugs rarely do this)

Palliative - treating/managing symptoms

Question 3

How can enantiomeric drugs have different effects?

Answer 3

• Sometimes 1 enantiomer may work over the other

- When put into sterile environment, they may act different

Question 4

How do drugs get to right tissue?

Answer 4

Have to pass blood brain barrier or be injected

Question 5

T/F: Drugs have to bind to receptors

Answer 5

False

Question 6

Define receptor

Answer 6

A structure or site on the surface or interior of cell that binds substances and initiates a biochemical event leading to a physiological response
- Located on membrane, cytoplasm, and nucleus

Question 7

What are examples of things receptors can bind to?

Answer 7

Hormones, antigens, drugs, neurotransmitters

Question 8

Define pharmacology

Answer 8

Study of drugs

Question 9

Define pharmodynamics

Answer 9

How does the drug affect the body?

Question 10

Define pharmacokinetics

Answer 10

What does the body do to the drug?

Question 11

Define pharmacogenomics/pharmacogenetics

Answer 11

Genetic variation that gives rise to differing response to drugs
- How we see the differences

Question 12

Define pharmacy

Answer 12

Science concerned with the manufacture, preparation, and dispensing of drugs

Question 13

Define pharmacotherapeutics

Answer 13

Prevention and treatment of disease

Question 14

Define pharmacognosy

Answer 14

Study of chemistry, activity, and use of natural compounds

Question 15

Define toxicology

Answer 15

Study of poisons

Question 16

Define pharmacovigilance

Answer 16

Study of surveillance of adverse effects and drug interactions

Question 17

Process for clinical trials

Answer 17

1. In vitro studies
2. Animal testing
3. Clinical testing (Phase 1: is it safe?. Phase 2: Does it work?. Phase 3: Does it work?)
4. Marketing (generic options become available)