14) Systematic Reviews

Question 1

Systematic reviews

Answer 1

Defined literature search
Thorough
- appraisal of individual studies identified
- summary of these studies 
- either descriptive OR metaanalysis

Question 2

MEtaanalysis

Answer 2

• stastical technique for combining data from multiple similar studies into a quantitative summary statistic

Question 3

Systematic reviews and metaanalysis

Answer 3

• not all systemtic reviews are metaanalysis and vice versa

Question 4

Why do we need systematic reviews

Answer 4

• increase power to detect intervention effects
• explore between study differences
• cope with the amount of medical literature
• systematic

Question 5

Appropriate inclusion criteria

Answer 5

Explicitely given before results analysed

• matched to research question asked
• methodological standards of included studies

Question 6

Complete data?

Answer 6

• poor search
• publication bias
• location bias
• duplication bias

Question 7

Will the treatment recomendation be clear from a systematic review?

Answer 7

• sometimes

Question 8

Should systematic reviews only be done on placebo-controlled trials?

Answer 8

• new treatments should always be compared to the best treatment available

Question 9

Is a meta analysis
A) a statistical technique for detecting bias?
B) A statistical technique for combining data from studies into a quantitative summary statistic
C) An analysis of meta data?

Answer 9

B) a statistical technique for combining data from studies into a quantitative summary statistic

Question 10

True or false: including data from a conderence abstract in a systematic review will introduce bias because the research has not been peer reviewes

Answer 10

False: its all about publication bias