13) Diagnostic And Screening Test 2

Question 1

Replacement test

Answer 1

• will have similar sensitivity and specificity as the existing test
• may have other advantages such as safety, ease of execution or interpretation

Question 2

Triage test

Answer 2

• doesnt matter as much if it incorrectly classifies someone without the disease, as thest positive because he will have the existing definitive test anyway

Question 3

Add-on test

Answer 3

• used to maximize overall sensitivity of dagnostic pathways
• often less accessible and more risky

Question 4

Baye’s theorem:

Answer 4

• post-test odds = pretest odds * likelihoood ratio
• pretest offs can be estimated using prevalence of disease in a similar clinical cohort in the literatyre, from your local database or clinical intuition
• likelihood ratio: expresses how likely a test result is to be found in disease compared with non-diseased people