1.4 Steps Of Fertilisation In Mammals Flashcards
Stage 1) CONTACT
Sperm come in contact with secondary oocyte
Calcium ions enter sperm head
Stimulates sperm to release Acrosome enzymes
Acrosomal reaction
Alkaline semen provides a medium for sperm to swim, also contains hormones called prostaglandins which stimulate contraction of the uterus and oviducts to assist the
Movement of the sperms
Stage 2) ACROSOMAL REACTION
Acrosome swells
Cell membrane of sperm fuses with the membrane of Acrosome
Contents flow out
Hydrolytic Enzymes released
Digest zona pellucida
Stage 3) ATTACHMENT OF SPERM TO OVUM
Sperm binds to the membrane of the ovum
Stage 4)
Fusion of sperm and ovum membrane
Stage 5) CORTICAL REACTION
cortical granules move towards the ovum membrane to release their contents into the zona pellucida
Hardens the zona pellucida - prevents polyspermy
Stage 6) FERTILISATION
The haploid sperm fuses with the haploid ovum nucleus to form diploid zygote nucleus